Dark Spot Correcting Serum 4% Niacinamide

Differin

Dark Spot Correcting Serum 4% Niacinamide

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About this product

The Differin Dark Spot Correcting Serum 4% Niacinamide is a serums, essence, ampoule. Our analysis of its 23 ingredients (19 low-risk) rates it Excellent (98/100). Based on its ingredients, it looks well-suited to oily / acne-prone skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
23
Low-risk
19
Fragrance
Contains fragrance
Origin
United States
Data updated
Jun 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 2/6
Good for dry skin
Hippophae Rhamnoides Oil Caprylyl Glycol
Caution for dry skin
Denatonium Benzoate t-Butyl Alcohol Alcohol Polysorbate 20 Polysorbate 60 PEG-40 Hydrogenated Castor Oil
Oily/Acne-Prone Skin 2/0
Good for oily/acne-prone skin
Sodium Ascorbyl Phosphate Alcohol
Sensitive Skin 3/6
Good for sensitive skin
Sodium Ascorbyl Phosphate Sodium Sulfite Sodium Metabisulfite
Caution for sensitive skin
Denatonium Benzoate Disodium Phosphate t-Butyl Alcohol Citric Acid Alcohol PEG-40 Hydrogenated Castor Oil

Ingredients list

23 total
Lower hazard (1) Higher hazard (4)
All23 Fragrance8 Skin Conditioning8 Masking4 Solvent4 Buffering Agent3 Viscosity Controlling3 Hair Conditioning3 Emulsifying3
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
2
Alcohol
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
3
B
PEG-40 Hydrogenated Castor Oil
(Fragrance, Emulsifying, Surfactant, Perfuming)
Fungal Acne
Fungal Acne Trigger
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
A
Hydroxyethylcellulose
(Binding Agent, Emulsion Stabilising, Film Forming, Viscosity Increasing Agent, Binding, Stabilising, Viscosity Controlling)
1
A
Sodium Ascorbyl Phosphate
(Antioxidant)
1
A
1,2-Hexanediol
(Solvent)
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
1
A
Hippophae Rhamnoides Oil
(Emollient, Skin Conditioning)
Fungal Acne
Fungal Acne Trigger
Helianthus Annuus Seed Oil
(Fragrance, Skin Conditioning, Skin Conditioning Emollient)
rosmarinus officinalis leaf extract
(Antimicrobial, Fragrance, Skin Conditioning)
1
A
Biotin
(Hair Conditioning, Skin Conditioning, Antiseborrhoeic)
4
A
Sodium Metabisulfite
(Antioxidant, Preservative, Reducing)
2
A
Sodium Sulfite
(Antioxidant, Hair Waving Or Straightening, Reducing, Preservative)
2
A
Citric Acid
(Chelating Agent, Fragrance, Ph Adjuster, Buffering Agent, Masking)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
2
A
t-Butyl Alcohol
(Denaturant, Fragrance, Solvent, Perfuming)
1
B
Disodium Phosphate
(Buffering Agent, Anticorrosive, Fragrance, Ph Adjuster, Masking)
3
B
Polysorbate 60
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
PARFUM
(Fragrance, Perfuming)
1
B
Sodium Phosphate
(Buffering Agent)
1
A
Denatonium Benzoate
(Denaturant, Fragrance, Masking)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Antioxidants
Shields skin from free radical damage.
Vitamin C
Brightens, evens tone, and supports collagen.
Niacinamide
Strengthens, smooths, and brightens skin.

Benefits

Redness ReducingSoothes visible redness and calms irritation.
HydratingBoosts hydration and relieves dry, tight skin.
BrighteningRestores radiance to dull, tired skin.
Reduces Large PoresMinimizes the look of enlarged pores.
Scar HealingImproves the look of marks and scars.
Skin TextureSmooths rough patches and refines texture.
Barrier RepairStrengthen and restore your skin's natural barrier.
Acne FightingFights acne and helps prevent breakouts.

Concerns

Not fungal acne (malassezia) safe
May not suit dry skin
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Hydroxyethylcellulose
Binding agent, Emulsion stabilising
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Binding agentEmulsion stabilisingFilm formingViscosity increasing agentBindingStabilisingViscosity controlling
Sodium Ascorbyl Phosphate
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antioxidant
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Caprylyl Glycol
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningEmollientHumectant
Helianthus Annuus Seed Oil
Fragrance, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A FragranceSkin conditioningSkin conditioning emollient
rosmarinus officinalis leaf extract
Antimicrobial, Fragrance
Limited public safety data.Read moreShow less
EWG N/A AntimicrobialFragranceSkin conditioning
Biotin
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningAntiseborrhoeic
Sodium Metabisulfite
Antioxidant, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A AntioxidantPreservativeReducing
Sodium Sulfite
Antioxidant, Hair waving or straightening
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A AntioxidantHair waving or straighteningReducingPreservative
Disodium EDTA
Chelating agent, Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Chelating agentViscosity controlling
t-Butyl Alcohol
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceSolventPerfuming
Disodium Phosphate
Buffering agent, Anticorrosive
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Buffering agentAnticorrosiveFragrancePh adjusterMasking
PARFUM
Fragrance, Perfuming
Limited public safety data.Read moreShow less
EWG N/A FragrancePerfuming
+ 2 more — see the full ingredients list above
Alcohol
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 2 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
PEG-40 Hydrogenated Castor Oil
Fragrance, Emulsifying
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B FragranceEmulsifyingSurfactantPerfuming Fungal-acne trigger
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Hippophae Rhamnoides Oil
Emollient, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientSkin conditioning Fungal-acne trigger
Citric Acid
Chelating agent, Fragrance
Skin irritation can occur at high concentrationRead moreShow less
EWG 2 CIR A Chelating agentFragrancePh adjusterBuffering agentMasking Bad for Sensitive Skin
Polysorbate 60
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Morning works well: Antioxidants like vitamin C pair well with daytime use under sunscreen.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

Sodium Ascorbyl Phosphate

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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