Mission: Skin Retinol 1% Defender Cream

DMD Skin Sciences

Mission: Skin Retinol 1% Defender Cream

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About this product

The DMD Skin Sciences Mission: Skin Retinol 1% Defender Cream is a treatment. Our analysis of its 19 ingredients (15 low-risk) rates it Excellent (90/100). Based on its ingredients, it looks well-suited to dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Treatments
Ingredients
19
Low-risk
15
Fragrance
Fragrance-free
Origin
Philippines
Data updated
Jun 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 6/4
Good for dry skin
Glyceryl Stearate Cetearyl Alcohol Glycerin Propylene Glycol Sodium Lactate Aloe Barbadensis Leaf Extract
Caution for dry skin
Stearic Acid Glycerin Ceteareth-20 Triethanolamine
Oily/Acne-Prone Skin No data
Sensitive Skin 3/6
Good for sensitive skin
Madecassoside Glycerin Aloe Barbadensis Leaf Extract
Caution for sensitive skin
Stearic Acid Glycerin Propylene Glycol Phenoxyethanol Triethanolamine Retinyl Acetate

Ingredients list

19 total
Lower hazard (1) Higher hazard (9)
All19 Skin Conditioning8 Humectant6 Solvent5 Fragrance5 Emulsifying5 Emulsion Stabilising4 Viscosity Controlling4 Emollient3
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
A
Stearic Acid
(Fragrance, Sufactant, Emulsifying, Surfactantsurfactant Cleansing Agent Is Included As A Function For The Soap Form Of Stearic Acid., Emulsion Stabilising, Masking, Refatting)
Bad for Oily Skin
Bad for Oily Skin
Fungal Acne
Fungal Acne Trigger
PARAFFINUM LIQUIDUM
(Antistatic, Skin Conditioning Emollient, Skin Protecting, Solvent)
1
A
Glyceryl Stearate
(Emollient, Emulsifying)
Fungal Acne
Fungal Acne Trigger
1
A
Cetearyl Alcohol
(Emulsion Stabilising, Opacifying, Foam Boosting, Viscosity Increasingagent Aqueous, Viscosity Increasing Agent, Emollient, Emulsifying, Viscosity Controlling)
3
B
Ceteareth-20
(Cleansing, Emulsifying, Surfactant)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
3
B
Sodium Lactate
(Buffering Agent, Exfoliant, Humectant, Keratolytic)
1
A
Sodium Gluconate
(Chelating Agent, Skin Conditioning)
9
Retinyl Acetate
(Skin Conditioning)
3
B
Propylene Glycol
(Fragrance, Humectant, Skin Conditioningagent Miscellaneous, Solvent, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
5
B
Triethanolamine
(Fragrance, Ph Adjuster, Emulsifying, Surfactant, Buffering Agent, Masking)
1
A
Panthenol
(Antistatic Agent, Hair Conditioning, Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
1
A
Pentylene Glycol
(Skin Conditioning, Solvent)
1
Madecassoside
(Antioxidant, Skin Conditioning)
1
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
(Emulsion Stabilising, Film Forming, Viscosity Controlling)
1
3
B
Aloe Barbadensis Leaf Extract
(Emollient, Humectant, Oral Care Agent, Skin Conditioning)
Good for Sensitive Skin
Good for Sensitive Skin
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Retinoid
Visibly reduces the signs of aging.
Antioxidants
Shields skin from free radical damage.

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Scar HealingImproves the look of marks and scars.
Barrier RepairStrengthen and restore your skin's natural barrier.
Reduces IrritationEases discomfort and supports skin resilience.
Redness ReducingSoothes visible redness and calms irritation.
Anti-AgingSoftens lines and helps skin look youthful.
BrighteningRestores radiance to dull, tired skin.
Dark SpotsFades dark spots for even skin tone.

Concerns

Contains paraben
Not fungal acne (malassezia) safe
Retinyl Acetate — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
PARAFFINUM LIQUIDUM
Antistatic, Skin conditioning emollient
Limited public safety data.Read moreShow less
EWG N/A AntistaticSkin conditioning emollientSkin protectingSolvent
Cetearyl Alcohol
Emulsion stabilising, Opacifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingOpacifyingFoam boostingViscosity increasingagent - aqueousViscosity increasing agentEmollientEmulsifyingViscosity controlling
Ceteareth-20
Cleansing, Emulsifying
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B CleansingEmulsifyingSurfactant
Sodium Lactate
Buffering agent, Exfoliant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B Buffering agentExfoliantHumectantKeratolytic
Sodium Gluconate
Chelating agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Chelating agentSkin conditioning
Pentylene Glycol
Skin conditioning, Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningSolvent
Madecassoside
Antioxidant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 AntioxidantSkin conditioning
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion stabilising, Film forming
Low-hazard ingredient.Read moreShow less
EWG 1 Emulsion stabilisingFilm formingViscosity controlling
Disodium EDTA
Chelating agent, Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Chelating agentViscosity controlling
Stearic Acid
Fragrance, Sufactant
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR A FragranceSufactantEmulsifyingSurfactantsurfactant-cleansing agent is included as a function for the soap form of stearic acid.Emulsion stabilisingMaskingRefatting Bad for Oily SkinFungal-acne trigger
Glyceryl Stearate
Emollient, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientEmulsifying Fungal-acne trigger
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Retinyl Acetate
Skin conditioning
Higher-hazard ingredient.Read moreShow less
EWG 9 Skin conditioning
Propylene Glycol
Fragrance, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B FragranceHumectantSkin-conditioningagent - miscellaneousSolventViscosity decreasing agentSkin conditioningViscosity controlling Good for Dry Skin
Triethanolamine
Fragrance, Ph adjuster
Moderate-hazard ingredient.Read moreShow less
EWG 5 CIR B FragrancePh adjusterEmulsifyingSurfactantBuffering agentMasking
Panthenol
Antistatic agent, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antistatic agentHair conditioningSkin conditioning Good for Dry Skin
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben
Aloe Barbadensis Leaf Extract
Emollient, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 1–3 CIR B EmollientHumectantOral care agentSkin conditioning Good for Sensitive Skin

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinyl Acetate)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinyl Acetate

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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