Dr. Denese New York Wrinkle Rx Extreme Pro-Peptide Gel

Dr. Denese New York

Dr. Denese New York Wrinkle Rx Extreme Pro-Peptide Gel

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About this product

The Dr. Denese New York Wrinkle Rx Extreme Pro-Peptide Gel is a treatment. Our analysis of its 50 ingredients (44 low-risk) rates it Excellent (98/100). Based on its ingredients, it looks well-suited to oily / acne-prone, dry, and sensitive skin.

Vegan-friendly

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Treatments
Ingredients
50
Low-risk
44
Fragrance
Fragrance-free
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 14/8
Good for dry skin
Glycyrrhiza Glabra (Licorice) Root Extract Glucose Glycereth-26 Dipotassium Glycyrrhizate Acetyl Hexapeptide-8 Caprylic/Capric Triglyceride Caprylyl Glycol Butylene Glycol Sodium Hyaluronate Glycerin Cyclomethicone Dimethicone Bis-PEG-18 Methyl Ether Dimethyl Silane Lecithin
Caution for dry skin
Lysolecithin Lonicera Caprifolium (Honeysuckle) Flower Extract Xanthan Gum Glycerin Polyglyceryl-10 Stearate Polyglyceryl-10 Oleate Polysorbate 20 Lecithin
Oily/Acne-Prone Skin 2/0
Good for oily/acne-prone skin
Sodium Ascorbyl Phosphate Lonicera Caprifolium (Honeysuckle) Flower Extract
Sensitive Skin 9/7
Good for sensitive skin
Glycyrrhiza Glabra (Licorice) Root Extract Sodium Ascorbyl Phosphate Ascorbyl Glucoside Caprooyl Tetrapeptide-3 Glycerin Haematococcus Pluvialis Extract Dimethicone Sodium Bisulfite Tocopheryl Acetate
Caution for sensitive skin
Glycyrrhiza Glabra (Licorice) Root Extract Lonicera Caprifolium (Honeysuckle) Flower Extract Caprylic/Capric Triglyceride Butylene Glycol Glycerin Citric Acid Phenoxyethanol

Ingredients list

50 total
Lower hazard (1) Higher hazard (6)
All50 Skin Conditioning38 Humectant13 Viscosity Controlling8 Solvent6 Emollient6 Hair Conditioning6 Antioxidant6 Emulsifying5
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
2
A
Cyclomethicone
(Antistatic Agent, Emollient, Hair Conditioning, Humectant, Solvent, Viscosity Controlling)
Silicone
Silicone
1
A
Sodium Ascorbyl Phosphate
(Antioxidant)
1
Glycereth-26
(Humectant, Viscosity Decreasing Agent, Solvent, Viscosity Controlling)
1
Ascorbyl Glucoside
(Antioxidant)
3
Bis-PEG-18 Methyl Ether Dimethyl Silane
(Humectant, Foam Boosting, Hydrotrope, Emollient, Hair Conditioning, Skin Conditioning)
A
Retinyl Palmitate/Carrot Polypeptide
(Skin Conditioning)
1
A
Dimethicone/Vinyl Dimethicone Crosspolymer
(Viscosity Controlling)
1
Caprooyl Tetrapeptide-3
(Skin Protecting)
1
A
Tripeptide-1
(Skin Conditioning)
1
Acetyl Hexapeptide-8
(Humectant, Skin Conditioning)
Acetyl Tetrapeptide-11
(Skin Conditioning)
1
Palmitoyl Tripeptide-5
(Skin Conditioning)
1
Palmitoyl Oligopeptide
(Skin Conditioning, Sufactant)
1
A
Palmitoyl Tetrapeptide-7
(Skin Conditioning)
1
Euterpe Oleracea Fruit Extract
(Hair Conditioning)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
B
Malus Domestica Fruit Cell Culture Extract
(Skin Conditioning)
1
Polysilicone-11
(Film Forming)
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
Tocopherol (Vitamin E) Good for Dry Skin
Good for Dry Skin
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
1
B
Hydrolyzed Wheat Protein
(Film Forming, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1
A
Dipotassium Glycyrrhizate
(Flavoring Agent, Skin Conditioning, Humectant)
1
Haematococcus Pluvialis Extract
(Antioxidant)
1
Astaxanthin
(Cosmetic Colorant, Skin Conditioning)
1
Lonicera Caprifolium (Honeysuckle) Flower Extract
(Astringent, Masking)
1
Zizyphus Jujuba Fruit Extract
(Skin Conditioning)
1
Glycyrrhiza Glabra (Licorice) Root Extract
(Antioxidant, Humectant, Skin Conditioning, Perfuming)
B
Citrus Aurantium Amara (Bitter Orange) Peel Oil
(Skin Conditioning)
2
3
Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Antistatic Agent, Emollient)
1
A
Dextran
(Binding Agent, Bulking Agent, Binding, Viscosity Controlling)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
2
Guanidine HCL
(Buffering Agent)
1
A
Lysolecithin
(Emulsifying, Surfactant)
1
A
Glucose
(Flavoring Agent, Humectant, Skin Conditioning Agent Miscellaneous)
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
1
B
Polyglyceryl-10 Oleate
(Skin Conditioning, Emulsifying, Surfactant)
1
B
Polyglyceryl-10 Stearate
(Skin Conditioning, Emulsifying, Surfactant)
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
3
B
Potassium Hydroxide
(Ph Adjuster, Buffering Agent)
2
A
Citric Acid
(Chelating Agent, Fragrance, Ph Adjuster, Buffering Agent, Masking)
Bad for Sensitive Skin
Bad for Sensitive Skin
6
Ethylhexyl Methoxycinnamate
(Uv Absorber, Uv Filter)
Bad for Oily Skin
Bad for Oily Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
3
A
Sodium Bisulfite
(Antioxidant, Hair Waving Or Straightening, Reducing, Preservative)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Cyclomethicone
Emollient, Humectant
Sodium Ascorbyl Phosphate
Antioxidant
Glycereth-26
Humectant
Ascorbyl Glucoside
Antioxidant
Bis-PEG-18 Methyl Ether Dimethyl Silane
Humectant, Emollient
Retinyl Palmitate/Carrot Polypeptide
Skin Conditioning

Benefits

Good for dry skin
Good for oily/acne-prone skin
Good for sensitive skin

Concerns

Contains paraben
Contains silicone
Not fungal acne (malassezia) safe

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Sodium Ascorbyl Phosphate
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antioxidant
Glycereth-26
Humectant, Viscosity decreasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 HumectantViscosity decreasing agentSolventViscosity controlling
Ascorbyl Glucoside
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 Antioxidant
Bis-PEG-18 Methyl Ether Dimethyl Silane
Humectant, Foam boosting
Low-to-moderate hazard.Read moreShow less
EWG 3 HumectantFoam boostingHydrotropeEmollientHair conditioningSkin conditioning
Retinyl Palmitate/Carrot Polypeptide
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A CIR A Skin conditioning
Dimethicone/Vinyl Dimethicone Crosspolymer
Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Viscosity controlling
Caprooyl Tetrapeptide-3
Skin protecting
Low-hazard ingredient.Read moreShow less
EWG 1 Skin protecting
Tripeptide-1
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Acetyl Hexapeptide-8
Humectant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 HumectantSkin conditioning
Acetyl Tetrapeptide-11
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Palmitoyl Tripeptide-5
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Palmitoyl Oligopeptide
Skin conditioning, Sufactant
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioningSufactant
Palmitoyl Tetrapeptide-7
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Euterpe Oleracea Fruit Extract
Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Hair conditioning
+ 24 more — see the full ingredients list above
Cyclomethicone
Antistatic agent, Emollient
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A Antistatic agentEmollientHair conditioningHumectantSolventViscosity controlling Silicone
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Tocopherol (Vitamin E)
Other
Low-hazard ingredient.Read moreShow less
EWG 1 Good for Dry Skin
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Citric Acid
Chelating agent, Fragrance
Skin irritation can occur at high concentrationRead moreShow less
EWG 2 CIR A Chelating agentFragrancePh adjusterBuffering agentMasking Bad for Sensitive Skin
Ethylhexyl Methoxycinnamate
Uv absorber, Uv filter
Potentially a skin irritantRead moreShow less
EWG 6 Uv absorberUv filter Bad for Oily SkinBad for Sensitive Skin
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Morning only: Apply as the last step of your AM routine, after moisturiser, and reapply every ~2 hours of sun exposure.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinyl Palmitate/Carrot Polypeptide)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinyl Palmitate/Carrot Polypeptide

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

Sodium Ascorbyl Phosphate, Ascorbyl Glucoside

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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