Hemp Super Serum

Dr. Denese SkinScience

Where to buy Possibly in stock

About this product

The Dr. Denese SkinScience Hemp Super Serum is a serums, essence, ampoule. Our analysis of its 27 ingredients (20 low-risk) rates it Excellent (100/100). Based on its ingredients, it looks well-suited to dry and sensitive skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
27
Low-risk
20
Fragrance
Fragrance-free
Origin
United States
Data updated
Jun 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 9/4
Good for dry skin
C12-15 Alkyl Benzoate C18-36 Acid Glycol Ester C18-36 Acid Triglyceride Ethoxydiglycol Caprylic/Capric Triglyceride Tribehenin Cannabis Sativa Seed Oil Dimethicone Cyclopentasiloxane
Caution for dry skin
C18-36 Acid Glycol Ester Dimethicone Crosspolymer Sorbitan Laurate PEG-10 Phytosterol
Oily/Acne-Prone Skin No data
Sensitive Skin 4/2
Good for sensitive skin
Melatonin Tetrahexyldecyl Ascorbate Dimethicone Tocopheryl Acetate
Caution for sensitive skin
Ethoxydiglycol Caprylic/Capric Triglyceride

Ingredients list

27 total
Lower hazard (1) Higher hazard (3)
All27 Skin Conditioning26 Emollient8 Solvent4 Surfactant3 Emulsifying3 Perfuming3 Fragrance3 Antioxidant3
EWG CIR Ingredient Name & Cosmetic Functions Notes
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone
3
A
Cyclopentasiloxane
(Hair Conditioning, Skin Conditioning, Emollient, Solvent)
Silicone
Silicone
1
Caprylyl Methicone
(Skin Conditioning)
1
A
Dimethicone Crosspolymer
(Emulsion Stabilising, Hair Fixing, Suspending Agent Nonsurfactant, Viscosity Increasingagent Nonaqueous, Viscosity Controlling)
2
Cannabis Sativa Seed Oil
(Emollient, Skin Conditioning)
Fungal Acne
Fungal Acne Trigger
1
Tetrahexyldecyl Ascorbate
(Antioxidant, Skin Conditioning)
Hydroxypinacolone Retinoate
(Skin Conditioning)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
Palmitoyl Hexapeptide-12
(Skin Conditioning)
1
Palmitoyl Hexapeptide-14
(Skin Conditioning)
1
A
Palmitoyl Tripeptide-1
(Skin Conditioning)
1
A
Palmitoyl Tetrapeptide-7
(Skin Conditioning)
1
Melatonin
(Antioxidant)
Ceramide NG
(Skin Conditioning)
Bisabolol
(Fragrance, Skin Conditioning, Soothing)
Zingiber Officinale Root Extract
(Fragrance, Perfuming, Skin Conditioning, Tonic)
Hydroxymethoxyphenyl Decanone
(Skin Conditioning)
1
A
C12-15 Alkyl Benzoate
(Skin Conditioning, Emollient, Antimicrobial)
1
Polysilicone-11
(Film Forming)
1
A
Ethoxydiglycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Humectant, Perfuming)
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
1
A
Sorbitan Laurate
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
C18-36 Acid Glycol Ester
(Skin Conditioning, Emollient, Emulsifying, Surfactant)
1
C18-36 Acid Triglyceride
(Emollient, Skin Conditioning)
1
A
Tribehenin
(Emollient, Skin Conditioning)
PEG-10 Phytosterol
(Emulsifying, Surfactant)
1
Dimethyl Isosorbide
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Peptides
Supports skin hydration and improves firmness.
Antioxidants
Shields skin from free radical damage.
Retinoid
Visibly reduces the signs of aging.
Vitamin C
Brightens, evens tone, and supports collagen.
Vitamin E
Protects skin and soothes irritation.
Ceramides
Locks in moisture and supports skin barrier.
Show all 6 key ingredients

Benefits

Scar HealingImproves the look of marks and scars.
Anti-AgingSoftens lines and helps skin look youthful.
Skin TextureSmooths rough patches and refines texture.
HydratingBoosts hydration and relieves dry, tight skin.
BrighteningRestores radiance to dull, tired skin.
Reduces IrritationEases discomfort and supports skin resilience.
Barrier RepairStrengthen and restore your skin's natural barrier.
Good For Oily SkinBalances oil and helps reduce shine.

Concerns

Contains silicone
Not fungal acne (malassezia) safe

Ingredients explained

Caprylyl Methicone
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Dimethicone Crosspolymer
Emulsion stabilising, Hair fixing
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingHair fixingSuspending agent - nonsurfactantViscosity increasingagent - nonaqueousViscosity controlling
Tetrahexyldecyl Ascorbate
Antioxidant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 AntioxidantSkin conditioning
Hydroxypinacolone Retinoate
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Palmitoyl Hexapeptide-12
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Palmitoyl Hexapeptide-14
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Palmitoyl Tripeptide-1
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Palmitoyl Tetrapeptide-7
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Melatonin
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 Antioxidant
Ceramide NG
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Bisabolol
Fragrance, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A FragranceSkin conditioningSoothing
Zingiber Officinale Root Extract
Fragrance, Perfuming
Limited public safety data.Read moreShow less
EWG N/A FragrancePerfumingSkin conditioningTonic
Hydroxymethoxyphenyl Decanone
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
C12-15 Alkyl Benzoate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningEmollientAntimicrobial
Polysilicone-11
Film forming
Low-hazard ingredient.Read moreShow less
EWG 1 Film forming
+ 7 more — see the full ingredients list above
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone
Cyclopentasiloxane
Hair conditioning, Skin conditioning
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Hair conditioningSkin conditioningEmollientSolvent Silicone
Cannabis Sativa Seed Oil
Emollient, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 2 EmollientSkin conditioning Fungal-acne trigger
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Sorbitan Laurate
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmulsifyingSurfactant Fungal-acne trigger

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Hydroxypinacolone Retinoate)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Hydroxypinacolone Retinoate

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

Tetrahexyldecyl Ascorbate

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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