Niacinamide 377 VC Brightening Serum
The Dr.Leo Niacinamide 377 VC Brightening Serum is a serums, essence, ampoule. Our analysis of its 55 ingredients (44 low-risk) rates it Excellent (99/100). Based on its ingredients, it looks well-suited to dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.
The Dr.Leo Niacinamide 377 VC Brightening Serum is a serums, essence, ampoule. Our analysis of its 55 ingredients (44 low-risk) rates it Excellent (99/100). Based on its ingredients, it looks well-suited to dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.
Summarised from our ingredient analysis — not brand marketing copy.
The evidence
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
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Water
(Solvent) |
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Dipropylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Masking, Viscosity Controlling) |
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Methyl Gluceth-20
(Humectant, Moisturising) |
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Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning) |
Silicone
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Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling) |
Good for Dry Skin
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Phenoxyethanol
(Fragrance, Preservative) |
Paraben
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Cornus Officinalis Fruit Extract
(Skin Conditioning) |
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Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent) |
Good for Dry Skin
Fungal Acne Trigger
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1,2-Hexanediol
(Solvent) |
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Ammonium Acryloyldimethyltaurate/VP Copolymer
(Viscosity Controlling) |
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Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing) |
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Hydroxyacetophenone
(Antioxidant) |
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1-Methylhydantoin-2-Imide
(Skin Conditioning) |
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Propanediol
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling) |
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Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling) |
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Tromethamine
(Fragrance, Ph Adjuster, Buffering Agent, Masking) |
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Polyacrylate Crosspolymer-6
(Emulsion Stabilising, Viscosity Controlling) |
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Sodium Polyacryloyldimethyl Taurate
(Emulsion Stabilising, Viscosity Increasing Agent, Viscosity Controlling) |
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Ethylhexylglycerin
(Deodorant, Skin Conditioning) |
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Arginine Ferulate
(Skin Conditioning) |
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Pentylene Glycol
(Skin Conditioning, Solvent) |
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Paeonia Albiflora Root Extract
(Skin Conditioning) |
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Disodium EDTA
(Chelating Agent, Viscosity Controlling) |
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Phaeodactylum Tricornutum Extract
(Humectant, Soothing) |
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PEG-40 Hydrogenated Castor Oil
(Fragrance, Emulsifying, Surfactant, Perfuming) |
Fungal Acne Trigger
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Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Antistatic Agent, Emollient) |
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Steareth-20
(Sufactant, Emulsifying, Surfactant) |
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Tremella Fuciformis Extract
(Humectant, Skin Conditioning) |
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Hydrogenated Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Suspending Agent Nonsurfactant) |
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Sodium Hyaluronate
(Skin Conditioning, Humectant) |
Good for Dry Skin
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Trideceth-9
(Emulsifying, Surfactant) |
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Sodium Ascorbate
(Antioxidant) |
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Magnolia Sieboldii Extract
(Skin Conditioning) |
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Tripeptide-1
(Skin Conditioning) |
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Ceramide NP
(Hair Conditioning, Skin Conditioning) |
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Sclareolide
(Masking, Perfuming, Skin Conditioning) |
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Phenylethyl Resorcinol
(Antioxidant) |
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Propylene Glycol
(Fragrance, Humectant, Skin Conditioningagent Miscellaneous, Solvent, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling) |
Good for Dry Skin
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Undecylenoyl Phenylalanine
(Skin Conditioning) |
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PARFUM
(Fragrance, Perfuming) |
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Mannitol
(Binding Agent, Flavoring Agent, Humectant, Binding, Masking, Moisturising, Skin Conditioning) |
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Acetyl Tetrapeptide-9
(Skin Conditioning) |
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Hexapeptide-9
(Skin Conditioning) |
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Glabridin
(Bleaching) |
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TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning) |
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Palmitoyl Pentapeptide-4
(Skin Conditioning) |
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Acetyl Hexapeptide-8
(Humectant, Skin Conditioning) |
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Palmitoyl Tetrapeptide-7
(Skin Conditioning) |
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Citric Acid
(Chelating Agent, Fragrance, Ph Adjuster, Buffering Agent, Masking) |
Bad for Sensitive Skin
|
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Ceramide NS
(Hair Conditioning, Skin Conditioning) |
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Ceramide AS
(Hair Conditioning, Skin Conditioning) |
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Ergothioneine
(Antioxidant) |
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Silica
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Opacifying, Viscosity Controlling) |
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Ceramide AP
(Hair Conditioning, Skin Conditioning) |
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Ceramide EOP
(Hair Conditioning, Skin Conditioning) |
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How to use
General guidance from this product's category and active ingredients — always follow the directions on the package.
Trust & honesty
The concentrations these actives are typically effective at in research — not a measurement of this product.
L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.
Sodium Ascorbate
Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.
Niacinamide
INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.
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