Retinol Vital Ampoule

ESFOLIO

Where to buy Possibly in stock

About this product

The ESFOLIO Retinol Vital Ampoule is a serums, essence, ampoule. Our analysis of its 60 ingredients (49 low-risk) rates it Excellent (98/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.

Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
60
Low-risk
49
Fragrance
Contains fragrance
Origin
South Korea

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 21/16
Good for dry skin
Glycosphingolipids Glutamic Acid Glycereth-26 Glyceryl Acrylate/Acrylic Acid Copolymer Linoleic Acid Macadamia Ternifolia Seed Oil Betaine Sucrose Stearate Inositol Caprylic/Capric Triglyceride Butylene Glycol Sodium PCA Sodium Hyaluronate Glycerin Cholesterol Trehalose Palmitic Acid Polyglyceryl-4 Caprate Tremella Fuciformis Sporocarp Extract Dimethicone Nelumbo Nucifera Phytoplacenta Culture Extract
Caution for dry skin
Linoleic Acid Sorbitan Sesquioleate Sucrose Stearate Stearic Acid Xanthan Gum Glycerin Palmitic Acid Potassium Cetyl Phosphate Polyglyceryl-4 Caprate Hydrogenated Phosphatidylcholine Ceteth-5 Alcohol Hydrogenated Lecithin Polysorbate 20 PEG-35 Castor Oil Ceteth-3
Oily/Acne-Prone Skin 2/0
Good for oily/acne-prone skin
Alcohol Retinol
Sensitive Skin 5/14
Good for sensitive skin
Glycerin Tremella Fuciformis Sporocarp Extract Dimethicone Tocopheryl Acetate Nelumbo Nucifera Phytoplacenta Culture Extract
Caution for sensitive skin
Glycine Glutamic Acid Dipropylene Glycol Linoleic Acid Serine Stearic Acid Alanine Arginine Caprylic/Capric Triglyceride Butylene Glycol Glycerin Palmitic Acid Alcohol Retinol

Ingredients list

60 total
Lower hazard (1) Higher hazard (9)
All60 Skin Conditioning50 Hair Conditioning18 Humectant15 Fragrance14 Antistatic Agent12 Emulsifying12 Viscosity Controlling11 Surfactant10
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
1
Glycereth-26
(Humectant, Viscosity Decreasing Agent, Solvent, Viscosity Controlling)
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone
Benzyl Glycol
(Solvent)
1
A
Sorbitan Sesquioleate
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
B
Betaine
(Hair Conditioning, Humectant, Antistatic Agent, Skin Conditioning, Viscosity Controlling)
1
B
Polyglyceryl-4 Caprate
(Skin Conditioning, Emollient, Emulsifying, Surfactant)
1
A
Arginine
(Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Masking)
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
PARFUM
(Fragrance, Perfuming)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
1
A
Trehalose
(Flavoring Agent, Humectant, Moisturising)
1
A
Panthenol
(Antistatic Agent, Hair Conditioning, Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
2
A
Chlorphenesin
(Cosmetic Biocide, Antimicrobial, Preservative)
1
A
1,2-Hexanediol
(Solvent)
1
Glyceryl Acrylate/Acrylic Acid Copolymer
(Humectant, Viscosity Controlling)
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
1
Adenosine
(Skin Conditioning)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
Nelumbo Nucifera Phytoplacenta Culture Extract
(Antimicrobial, Antioxidant, Hair Conditioning, Humectant)
1
A
Dipropylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Masking, Viscosity Controlling)
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
1
A
PVM/MA Copolymer
(Antistatic Agent, Binding, Emulsion Stabilising, Film Forming, Hair Fixing, Viscosity Controlling)
5
PEG-35 Castor Oil
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
Citrus Limon Fruit Extract
(Fragrance, Skin Conditioning)
2
Alcohol
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Hydrogenated Phosphatidylcholine
(Skin Conditioning, Emulsifying, Surfactant)
Aesculus Hippocastanum Seed Extract
(Skin Conditioning)
1
Macadamia Ternifolia Seed Oil
(Emollient)
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
2
A
Hydrogenated Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Suspending Agent Nonsurfactant)
1
B
Sodium PCA
(Hair Conditioning, Humectant, Antistatic Agent, Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
1
A
Serine
(Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Masking)
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
Tremella Fuciformis Sporocarp Extract
(Antioxidant, Hair Conditioning, Humectant, Skin Conditioning)
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
1
A
Glycine
(Buffering Agent, Fragrance, Hair Conditioning, Skin Conditioning Agent Miscellaneous, Antistatic Agent, Skin Conditioning)
1
A
Cholesterol
(Emulsion Stabilising, Skin Conditioning, Viscosity Increasing Agent, Emollient, Emulsifying, Stabilising, Viscosity Controlling)
1
Ceramide NP
(Hair Conditioning, Skin Conditioning)
1
A
Alanine
(Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Masking)
Brassica Campestris Sterols
(Skin Conditioning, Skin Conditioning Emollient)
1
A
Glutamic Acid
(Fragrance, Hair Conditioning, Humectant, Antistatic Agent)
2
B
Ceteth-5
(Emulsifying, Surfactant)
B
Ceteth-3
(Emulsifying, Surfactant)
1
Inositol
(Antistatic Agent, Hair Conditioning, Humectant)
Retinyl Palmitate
(Skin Conditioning, Skin Conditioning Miscellaneous)
1
Calcium Pantothenate
(Antistatic Agent, Hair Conditioning)
1
B
Potassium Cetyl Phosphate
(Emulsifying, Surfactant)
1
Linoleic Acid
(Fragrance, Hair Conditioning, Skin Conditioning, Sufactantsurfactant Cleansing Agent Is Included As A Function For The Soap Form Of Linoleic Acid., Antistatic Agent, Emollient)
Fungal Acne
Fungal Acne Trigger
1
Sucrose Stearate
(Skin Conditioning, Emollient, Emulsifying, Surfactant)
1
A
Stearic Acid
(Fragrance, Sufactant, Emulsifying, Surfactantsurfactant Cleansing Agent Is Included As A Function For The Soap Form Of Stearic Acid., Emulsion Stabilising, Masking, Refatting)
Bad for Oily Skin
Bad for Oily Skin
Fungal Acne
Fungal Acne Trigger
1
Phytosphingosine
(Hair Conditioning, Skin Conditioning)
1
A
Palmitic Acid
(Fragrance, Opacifying, Sufactant, Surfactant Emulsifying Agentsurfactant Cleansing Agent Is Included As A Function For The Soap Form Of Palmitic Acid., Emollient)
Bad for Oily Skin
Bad for Oily Skin
Fungal Acne
Fungal Acne Trigger
1
Glycosphingolipids
(Skin Conditioning, Emollient)
1
A
Biotin
(Hair Conditioning, Skin Conditioning, Antiseborrhoeic)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Antioxidants
Shields skin from free radical damage.
Retinoid
Visibly reduces the signs of aging.
Vitamin E
Protects skin and soothes irritation.
Niacinamide
Strengthens, smooths, and brightens skin.
Ceramides
Locks in moisture and supports skin barrier.
Hyaluronic Acid
Hydrates by attracting and holding water.
Show all 6 key ingredients

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Barrier RepairStrengthen and restore your skin's natural barrier.
Reduces IrritationEases discomfort and supports skin resilience.
Scar HealingImproves the look of marks and scars.
Anti-AgingSoftens lines and helps skin look youthful.
Redness ReducingSoothes visible redness and calms irritation.
BrighteningRestores radiance to dull, tired skin.
Dark SpotsFades dark spots for even skin tone.

Concerns

Contains silicone
Not fungal acne (malassezia) safe
Retinol — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Glycereth-26
Humectant, Viscosity decreasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 HumectantViscosity decreasing agentSolventViscosity controlling
Benzyl Glycol
Solvent
Limited public safety data.Read moreShow less
EWG N/A Solvent
Betaine
Hair conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Hair conditioningHumectantAntistatic agentSkin conditioningViscosity controlling
Polyglyceryl-4 Caprate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioningEmollientEmulsifyingSurfactant
Arginine
Fragrance, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceHair conditioningSkin conditioningAntistatic agentMasking
Carbomer
Emulsion stabilising, Viscosity increasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingViscosity increasing agentGel formingViscosity controlling
PARFUM
Fragrance, Perfuming
Limited public safety data.Read moreShow less
EWG N/A FragrancePerfuming
Trehalose
Flavoring agent, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Flavoring agentHumectantMoisturising
Chlorphenesin
Cosmetic biocide, Antimicrobial
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A Cosmetic biocideAntimicrobialPreservative
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Glyceryl Acrylate/Acrylic Acid Copolymer
Humectant, Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 HumectantViscosity controlling
Xanthan Gum
Binding agent, Emulsion stabilising
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Binding agentEmulsion stabilisingSkin conditioningSurfactant -emulsifying agentViscosity increasing agentBindingGel formingViscosity controlling
Adenosine
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
+ 30 more — see the full ingredients list above
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone
Sorbitan Sesquioleate
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmulsifyingSurfactant Fungal-acne trigger
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Panthenol
Antistatic agent, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antistatic agentHair conditioningSkin conditioning Good for Dry Skin
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
PEG-35 Castor Oil
Emulsifying, Surfactant
Moderate-hazard ingredient.Read moreShow less
EWG 5 EmulsifyingSurfactant Fungal-acne trigger
Alcohol
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 2 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Sodium PCA
Hair conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Hair conditioningHumectantAntistatic agentSkin conditioning Good for Dry Skin
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Linoleic Acid
Fragrance, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceHair conditioningSkin conditioningSufactantsurfactant-cleansing agent is included as a function for the soap form of linoleic acid.Antistatic agentEmollient Fungal-acne trigger
Stearic Acid
Fragrance, Sufactant
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR A FragranceSufactantEmulsifyingSurfactantsurfactant-cleansing agent is included as a function for the soap form of stearic acid.Emulsion stabilisingMaskingRefatting Bad for Oily SkinFungal-acne trigger
Palmitic Acid
Fragrance, Opacifying
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR A FragranceOpacifyingSufactantSurfactant -emulsifying agentsurfactant-cleansing agent is included as a function for the soap form of palmitic acid.Emollient Bad for Oily SkinFungal-acne trigger

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol, Retinyl Palmitate)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol, Retinyl Palmitate

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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