Estee Lauder Clear Difference Advanced Blemish Serum

Estee Lauder

Estee Lauder Clear Difference Advanced Blemish Serum

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About this product

The Estee Lauder Clear Difference Advanced Blemish Serum is a serums, essence, ampoule. Our analysis of its 30 ingredients (24 low-risk) rates it Excellent (91/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
30
Low-risk
24
Fragrance
Contains fragrance
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 7/7
Good for dry skin
Algae Extract Sucrose Isodecyl Neopentanoate Isohexadecane Butylene Glycol Sodium Hyaluronate Dimethicone
Caution for dry skin
Salicylic Acid Sodium Hydroxide Steareth-2 Steareth-21 Polysorbate 80 Benzalkonium Chloride Hamamelis Virginiana (Witch Hazel) Water
Oily/Acne-Prone Skin 2/0
Good for oily/acne-prone skin
Salicylic Acid Hamamelis Virginiana (Witch Hazel) Water
Sensitive Skin 5/8
Good for sensitive skin
Laminaria Saccharina Extract Sucrose Dimethicone Tocopheryl Acetate Hamamelis Virginiana (Witch Hazel) Water
Caution for sensitive skin
Algae Extract Glycine Caffeine Butylene Glycol Salicylic Acid Phenoxyethanol Linalool Fragrance

Ingredients list

30 total
Lower hazard (1) Higher hazard (8)
All30 Skin Conditioning25 Fragrance7 Masking5 Hair Conditioning4 Humectant4 Emollient4 Viscosity Controlling3 Antistatic Agent3
EWG CIR Ingredient Name & Cosmetic Functions Notes
4
B
Salicylic Acid
(Antiacne Agent, Antidandruff Agent, Corn/Callus/Wart Remover, Denaturant, Exfoliant, Fragrance, Hair Conditioning, Skin Conditioning, Keratolytic, Masking, Preservative)
Good for Oily Skin
Good for Oily Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone
1
Hamamelis Virginiana (Witch Hazel) Water
(Drug Astringent Skin Protecting, Skin Conditioning)
Good for Oily Skin
Good for Oily Skin
1
B
PPG-14 Butyl Ether
(Hair Conditioning, Skin Conditioning)
1
Acetyl Glucosamine
(Skin Conditioning)
1
A
Sucrose
(Flavoring Agent, Humectant, Skin Conditioning, Soothing)
1
B
Isodecyl Neopentanoate
(Skin Conditioning, Emollient)
3
B
Steareth-21
(Sufactant, Emulsifying, Surfactant)
1
A
Glycine
(Buffering Agent, Fragrance, Hair Conditioning, Skin Conditioning Agent Miscellaneous, Antistatic Agent, Skin Conditioning)
2
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
(Emulsion Stabilising, Viscosity Controlling)
1
Laminaria Digitata
1
Laminaria Saccharina Extract
(Skin Protecting)
1
Caffeine
(Fragrance, Skin Conditioning, Masking)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
1
B
Isohexadecane
(Skin Conditioning, Emollient, Solvent)
3
B
Steareth-2
(Emulsifying, Surfactant)
1
Algae Extract
(Fragrance, Humectant, Oral Care Agent, Skin Conditioning, Emollient)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
3
B
Polysorbate 80
(Denaturant, Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
A
Quaternium-22
(Antistatic Agent, Film Forming, Hair Conditioning)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
3
B
Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent)
1
A
Pentylene Glycol
(Skin Conditioning, Solvent)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
8
Fragrance
(Deodorant, Masking, Perfuming)
5
Linalool
(Fragrance, Deodorant, Masking)
Allergens
Allergens
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
4
B
Benzalkonium Chloride
(Antimicrobial Agent, Antistatic Agent, Cosmetic Biocide, Deodorant, Surfactant Suspending Agent, Preservative)
1
Green 3
Yellow 5 Lake

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Salicylic Acid
Exfoliant, Skin Conditioning
Dimethicone
Skin Protecting, Emollient
Hamamelis Virginiana (Witch Hazel) Water
Skin Conditioning
PPG-14 Butyl Ether
Skin Conditioning
Acetyl Glucosamine
Skin Conditioning
Sucrose
Humectant, Skin Conditioning

Benefits

Good for oily/acne-prone skin

Concerns

Contains paraben
Contains silicone
Contains eu allergen
Not fungal acne (malassezia) safe
Fragrance — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

PPG-14 Butyl Ether
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Hair conditioningSkin conditioning
Acetyl Glucosamine
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Sucrose
Flavoring agent, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Flavoring agentHumectantSkin conditioningSoothing
Isodecyl Neopentanoate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioningEmollient
Steareth-21
Sufactant, Emulsifying
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B SufactantEmulsifyingSurfactant
Glycine
Buffering agent, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Buffering agentFragranceHair conditioningSkin-conditioning agent -miscellaneousAntistatic agentSkin conditioning
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Emulsion stabilising, Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 2 Emulsion stabilisingViscosity controlling
Laminaria Digitata
Other
Low-hazard ingredient.Read moreShow less
EWG 1
Laminaria Saccharina Extract
Skin protecting
Low-hazard ingredient.Read moreShow less
EWG 1 Skin protecting
Caffeine
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceSkin conditioningMasking
Isohexadecane
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioningEmollientSolvent
Steareth-2
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant
Algae Extract
Fragrance, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceHumectantOral care agentSkin conditioningEmollient
Quaternium-22
Antistatic agent, Film forming
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antistatic agentFilm formingHair conditioning
Sodium Hydroxide
Denaturant, Ph adjuster
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B DenaturantPh adjusterBuffering agent
+ 5 more — see the full ingredients list above
Salicylic Acid
Antiacne agent, Antidandruff agent
Skin irritation can occur at high concentrationRead moreShow less
EWG 4 CIR B Antiacne agentAntidandruff agentCorn/callus/wart removerDenaturantExfoliantFragranceHair conditioningSkin conditioningKeratolyticMaskingPreservative Good for Oily SkinBad for Sensitive Skin
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone
Hamamelis Virginiana (Witch Hazel) Water
Drug astringent - skin protecting, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Drug astringent - skin protectingSkin conditioning Good for Oily Skin
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Polysorbate 80
Denaturant, Emulsifying
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B DenaturantEmulsifyingSurfactant Fungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Fragrance
Deodorant, Masking
Higher-hazard ingredient.Read moreShow less
EWG 8 DeodorantMaskingPerfuming
Linalool
Fragrance, Deodorant
Moderate-hazard ingredient.Read moreShow less
EWG 5 FragranceDeodorantMasking Allergens
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening, start slow: Best in the PM a few times a week to begin with; avoid layering with other strong actives the same night.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Use with caution
BHA (salicylic) (Salicylic Acid)

Low-strength topical salicylic acid (BHA) is generally considered fine. Caution is usually reserved for high-strength leave-on products and salicylic peels.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

BHA (salicylic) 0.5–2%

Salicylic acid is OTC-capped at 2%; 0.5–2% is the usual leave-on range. Much below that it acts more as a soothing agent than an exfoliant.

Salicylic Acid

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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