Collagen VC Tangle Ampoule

I.ST

Where to buy Possibly in stock

About this product

The I.ST Collagen VC Tangle Ampoule is a serums, essence, ampoule. Our analysis of its 34 ingredients (24 low-risk) rates it Excellent (100/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.

Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
34
Low-risk
24
Fragrance
Contains fragrance
Origin
South Korea

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 11/4
Good for dry skin
Moringa Oleifera Seed Oil Rosa Canina Fruit Oil Caprylic/Capric Triglyceride Caprylyl Glycol Butylene Glycol Glycerin Coco-Caprylate/Caprate Hydrolyzed Collagen Sucrose Pentaerucate Carnitine HCl Polyglyceryl-10 Decaisostearate
Caution for dry skin
Xanthan Gum Glycerin Sucrose Pentaerucate Tranexamic Acid
Oily/Acne-Prone Skin 1/0
Good for oily/acne-prone skin
Tranexamic Acid
Sensitive Skin 2/5
Good for sensitive skin
Melia Azadirachta Leaf Extract Glycerin
Caution for sensitive skin
Sodium Chloride Caprylic/Capric Triglyceride Butylene Glycol Glycerin Thiamine HCl

Ingredients list

34 total
Lower hazard (1) Higher hazard (2)
All34 Skin Conditioning34 Emollient8 Hair Conditioning7 Humectant6 Fragrance5 Solvent5 Masking4 Viscosity Controlling4
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
A
1,2-Hexanediol
(Solvent)
Polyglyceryl-10 Decaisostearate
(Emollient)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
1
Sodium Chloride
(Bulking Agent, Masking, Oral Care Agent, Viscosity Controlling)
1
A
Rosa Canina Fruit Oil
(Emollient, Skin Conditioning)
1
A
Hydrolyzed Collagen
(Hair Conditioning, Nail Conditioning Agent, Skin Conditioning, Antistatic Agent, Emollient, Film Forming, Humectant)
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
1
A
Panthenol
(Antistatic Agent, Hair Conditioning, Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
1
Adenosine
(Skin Conditioning)
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
1
Eclipta Prostrata Extract
(Skin Conditioning)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
Sucrose Pentaerucate
(Emollient, Emulsifying, Skin Conditioning, Surfactant)
Tranexamic Acid
(Cosmetic Astringent, Skin Conditioning)
1
Melia Azadirachta Leaf Extract
(Antimicrobial, Skin Protecting)
1
B
Coco-Caprylate/Caprate
(Emollient, Skin Conditioning)
1
Hippophae Rhamnoides Fruit Extract
(Skin Conditioning)
1
A
Moringa Oleifera Seed Oil
(Emollient, Skin Conditioning)
1
Caprylhydroxamic Acid
(Chelating Agent)
Retinyl Palmitate
(Skin Conditioning, Skin Conditioning Miscellaneous)
1
Riboflavin
(Cosmetic Colorant, Skin Conditioning)
1
A
Biotin
(Hair Conditioning, Skin Conditioning, Antiseborrhoeic)
ASCORBIC ACID
(Antioxidant, Buffering, Fragrance, Skin Conditioning)
B
Carnitine HCl
(Humectant, Skin Conditioning)
Thiamine HCl
(Masking, Skin Conditioning)
A
Pantothenic Acid
(Antistatic Agent, Hair Conditioning, Skin Conditioning)
1
Folic Acid
(Skin Conditioning)
PARFUM
(Fragrance, Perfuming)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Antioxidants
Shields skin from free radical damage.
Retinoid
Visibly reduces the signs of aging.
Vitamin C
Brightens, evens tone, and supports collagen.
Vitamin E
Protects skin and soothes irritation.
Niacinamide
Strengthens, smooths, and brightens skin.
Tranexamic Acid
Helps fade dark spots and even skin tone.
Show all 6 key ingredients

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Reduces IrritationEases discomfort and supports skin resilience.
Scar HealingImproves the look of marks and scars.
Barrier RepairStrengthen and restore your skin's natural barrier.
Anti-AgingSoftens lines and helps skin look youthful.
BrighteningRestores radiance to dull, tired skin.
Redness ReducingSoothes visible redness and calms irritation.
Dark SpotsFades dark spots for even skin tone.

Concerns

Not fungal acne (malassezia) safe
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Polyglyceryl-10 Decaisostearate
Emollient
Limited public safety data.Read moreShow less
EWG N/A Emollient
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Sodium Chloride
Bulking agent, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 Bulking agentMaskingOral care agentViscosity controlling
Rosa Canina Fruit Oil
Emollient, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientSkin conditioning
Hydrolyzed Collagen
Hair conditioning, Nail conditioning agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningNail conditioning agentSkin conditioningAntistatic agentEmollientFilm formingHumectant
Xanthan Gum
Binding agent, Emulsion stabilising
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Binding agentEmulsion stabilisingSkin conditioningSurfactant -emulsifying agentViscosity increasing agentBindingGel formingViscosity controlling
Ethylhexylglycerin
Deodorant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A DeodorantSkin conditioning
Caprylyl Glycol
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningEmollientHumectant
Adenosine
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
TOCOPHEROL
Antioxidant, Fragrance
Limited public safety data.Read moreShow less
EWG N/A AntioxidantFragranceSkin conditioning
Disodium EDTA
Chelating agent, Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Chelating agentViscosity controlling
Eclipta Prostrata Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
+ 16 more — see the full ingredients list above
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Panthenol
Antistatic agent, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antistatic agentHair conditioningSkin conditioning Good for Dry Skin
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinyl Palmitate)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinyl Palmitate

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

ASCORBIC ACID

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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