iS Clinical Poly-Vitamin Serum

iS Clinical

Where to buy Possibly in stock

About this product

The iS Clinical Poly-Vitamin Serum is a serums, essence, ampoule. Our analysis of its 13 ingredients (9 low-risk) rates it Excellent (85/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
13
Low-risk
9
Fragrance
Fragrance-free
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe Minimal Ingredients

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 3/3
Good for dry skin
Saccharum Officinarum (Sugar Cane) Extract Sodium Hyaluronate Camellia Sinensis (Green Tea) Leaf Extract
Caution for dry skin
Vaccinium Myrtillus (Bilberry) Extract Camellia Sinensis (Green Tea) Leaf Extract Zinc Sulfate
Oily/Acne-Prone Skin 4/0
Good for oily/acne-prone skin
Vaccinium Myrtillus (Bilberry) Extract Camellia Sinensis (Green Tea) Leaf Extract Zinc Sulfate Retinol
Sensitive Skin 1/5
Good for sensitive skin
Camellia Sinensis (Green Tea) Leaf Extract
Caution for sensitive skin
Glutamine Lysine Camellia Sinensis (Green Tea) Leaf Extract Phenoxyethanol Retinol

Ingredients list

13 total
Lower hazard (1) Higher hazard (9)
All13 Skin Conditioning14 Hair Conditioning4 Fragrance4 Antistatic Agent3 Humectant2 Oral Care Agent2 Antimicrobial2 Uv Absorber2
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
1
Saccharum Officinarum (Sugar Cane) Extract
(Skin Conditioning, Moisturising)
4
Zinc Sulfate
(Cosmetic Astringent, Cosmetic Biocide, Oral Care Agent, Antimicrobial, Antiplaque)
A
Pantothenic Acid
(Antistatic Agent, Hair Conditioning, Skin Conditioning)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
1
Tocopherol (Vitamin E) Good for Dry Skin
Good for Dry Skin
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Lysine
(Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1
A
Glutamine
(Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent)
1
Vaccinium Myrtillus (Bilberry) Extract
(Skin Conditioning, Astringent, Refreshing, Tonic)
2
Camellia Sinensis (Green Tea) Leaf Extract
(Antioxidant, Fragrance, Oral Care Agent, Skin Conditioning Agent Miscellaneous, Uv Absorber, Antimicrobial, Astringent, Emollient, Humectant, Masking, Skin Conditioning, Skin Protecting, Tonic)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Sodium Hyaluronate
Skin Conditioning, Humectant
Saccharum Officinarum (Sugar Cane) Extract
Skin Conditioning, Moisturising
Pantothenic Acid
Skin Conditioning
Niacinamide
Skin Conditioning
Retinol
Skin Conditioning
Lysine
Skin Conditioning

Benefits

Fungal-acne (Malassezia) safe
Good for oily/acne-prone skin

Concerns

Contains paraben
Retinol — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Saccharum Officinarum (Sugar Cane) Extract
Skin conditioning, Moisturising
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioningMoisturising
Zinc Sulfate
Cosmetic astringent, Cosmetic biocide
Low-to-moderate hazard.Read moreShow less
EWG 4 Cosmetic astringentCosmetic biocideOral care agentAntimicrobialAntiplaque
Pantothenic Acid
Antistatic agent, Hair conditioning
Limited public safety data.Read moreShow less
EWG N/A CIR A Antistatic agentHair conditioningSkin conditioning
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Lysine
Fragrance, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceHair conditioningSkin conditioningAntistatic agent
Glutamine
Fragrance, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceHair conditioningSkin conditioningAntistatic agent
Vaccinium Myrtillus (Bilberry) Extract
Skin conditioning, Astringent
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioningAstringentRefreshingTonic
Camellia Sinensis (Green Tea) Leaf Extract
Antioxidant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 AntioxidantFragranceOral care agentSkin-conditioning agent -miscellaneousUv absorberAntimicrobialAstringentEmollientHumectantMaskingSkin conditioningSkin protectingTonic
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Tocopherol (Vitamin E)
Other
Low-hazard ingredient.Read moreShow less
EWG 1 Good for Dry Skin
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Morning only: Apply as the last step of your AM routine, after moisturiser, and reapply every ~2 hours of sun exposure.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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