Retinal Smooth

ISDIN

Where to buy Possibly in stock

About this product

The ISDIN Retinal Smooth is a serums, essence, ampoule. Our analysis of its 44 ingredients (37 low-risk) rates it Excellent (98/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
44
Low-risk
37
Fragrance
Contains fragrance
Origin
Spain

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 9/9
Good for dry skin
C12-15 Alkyl Benzoate C18-36 Acid Glycol Ester C18-36 Acid Triglyceride Isoamyl Laurate Caprylic/Capric Triglyceride Caprylyl Glycol Glycerin Dibutyl Adipate Dimethicone
Caution for dry skin
C18-36 Acid Glycol Ester Maltodextrin Sorbitan Laurate Xanthan Gum Glycerin t-Butyl Alcohol Alcohol Denat. Silica Sodium Acrylates Crosspolymer-2
Oily/Acne-Prone Skin 1/0
Good for oily/acne-prone skin
Alcohol Denat.
Sensitive Skin 6/9
Good for sensitive skin
Melatonin Glycerin Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate Hydroxyacetophenone Dimethicone Tocopheryl Acetate
Caution for sensitive skin
Ethylcellulose Isoamyl Laurate Caprylic/Capric Triglyceride Glycerin 4-t-Butylcyclohexanol t-Butyl Alcohol Citric Acid Sodium Benzoate Alcohol Denat.

Ingredients list

44 total
Lower hazard (1) Higher hazard (6)
All44 Skin Conditioning32 Viscosity Controlling10 Solvent9 Fragrance9 Emollient8 Antioxidant6 Emulsion Stabilising5 Film Forming5
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone
1
A
Dibutyl Adipate
(Plasticizer, Skin Conditioning, Emollient, Solvent, Film Forming)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
1
B
Isoamyl Laurate
(Fragrance, Skin Conditioning, Emollient)
3
A
Lauryl PEG/PPG-18/18 Methicone
(Skin Conditioning)
1
A
C12-15 Alkyl Benzoate
(Skin Conditioning, Emollient, Antimicrobial)
1
Propanediol
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1
A
Dimethicone/Vinyl Dimethicone Crosspolymer
(Viscosity Controlling)
4
Alcohol Denat.
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
1,2-Hexanediol
(Solvent)
1
A
Pentylene Glycol
(Skin Conditioning, Solvent)
1
A
Ethylcellulose
(Binding Agent, Film Forming, Fragrance, Viscosity Increasing Agent, Binding, Viscosity Controlling)
1
Hydroxyacetophenone
(Antioxidant)
1
A
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
(Antioxidant)
1
4-t-Butylcyclohexanol
(Masking, Perfuming)
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
PARFUM
(Fragrance, Perfuming)
Sodium Acrylates Crosspolymer-2
(Absorbent)
1
Polyacrylate Crosspolymer-6
(Emulsion Stabilising, Viscosity Controlling)
1
Vigna Aconitifolia Seed Extract
(Skin Conditioning)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
3
A
Sodium Benzoate
(Fragrance, Preservative, Anticorrosive, Masking)
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
2
A
Citric Acid
(Chelating Agent, Fragrance, Ph Adjuster, Buffering Agent, Masking)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
1
A
Sorbitan Laurate
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
A
Maltodextrin
(Absorbent, Binding Agent, Emulsion Stabilising, Film Forming, Hair Conditioning, Skin Conditioning, Suspending Agent Nonsurfactant, Binding)
1
Melatonin
(Antioxidant)
1
2
A
Silica
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Opacifying, Viscosity Controlling)
1
C18-36 Acid Glycol Ester
(Skin Conditioning, Emollient, Emulsifying, Surfactant)
1
C18-36 Acid Triglyceride
(Emollient, Skin Conditioning)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
1
A
Synthetic Fluorphlogopite
(Bulking Agent, Viscosity Increasing Agent, Viscosity Controlling)
CI 77891
(Colorant)
5
6
Retinal
(Skin Conditioning)
1
A
Phospholipids
(Skin Conditioning)
2
A
t-Butyl Alcohol
(Denaturant, Fragrance, Solvent, Perfuming)
ASCORBIC ACID
(Antioxidant, Buffering, Fragrance, Skin Conditioning)
2
A
Tin Oxide
(Abrasive, Bulking Agent, Opacifying, Viscosity Controlling)
1
A
Palmitoyl Tripeptide-1
(Skin Conditioning)
1
A
Palmitoyl Tetrapeptide-7
(Skin Conditioning)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Antioxidants
Shields skin from free radical damage.
Vitamin E
Protects skin and soothes irritation.
Peptides
Supports skin hydration and improves firmness.
Exfoliators
Removes dead skin cells to smoothe texture.
Retinoid
Visibly reduces the signs of aging.
Vitamin C
Brightens, evens tone, and supports collagen.
Niacinamide
Strengthens, smooths, and brightens skin.
Show all 7 key ingredients

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Scar HealingImproves the look of marks and scars.
Barrier RepairStrengthen and restore your skin's natural barrier.
Anti-AgingSoftens lines and helps skin look youthful.
BrighteningRestores radiance to dull, tired skin.
Skin TextureSmooths rough patches and refines texture.
Redness ReducingSoothes visible redness and calms irritation.
Dark SpotsFades dark spots for even skin tone.

Concerns

Contains silicone
Not fungal acne (malassezia) safe
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Dibutyl Adipate
Plasticizer, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A PlasticizerSkin conditioningEmollientSolventFilm forming
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Isoamyl Laurate
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B FragranceSkin conditioningEmollient
Lauryl PEG/PPG-18/18 Methicone
Skin conditioning
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Skin conditioning
C12-15 Alkyl Benzoate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningEmollientAntimicrobial
Propanediol
Solvent, Viscosity decreasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 SolventViscosity decreasing agentViscosity controlling
Dimethicone/Vinyl Dimethicone Crosspolymer
Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Viscosity controlling
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Pentylene Glycol
Skin conditioning, Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningSolvent
Ethylcellulose
Binding agent, Film forming
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Binding agentFilm formingFragranceViscosity increasing agentBindingViscosity controlling
Hydroxyacetophenone
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 Antioxidant
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antioxidant
4-t-Butylcyclohexanol
Masking, Perfuming
Low-hazard ingredient.Read moreShow less
EWG 1 MaskingPerfuming
Caprylyl Glycol
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningEmollientHumectant
+ 22 more — see the full ingredients list above
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone
Alcohol Denat.
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 4 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Citric Acid
Chelating agent, Fragrance
Skin irritation can occur at high concentrationRead moreShow less
EWG 2 CIR A Chelating agentFragrancePh adjusterBuffering agentMasking Bad for Sensitive Skin
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Sorbitan Laurate
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmulsifyingSurfactant Fungal-acne trigger
Retinal
Skin conditioning
Moderate-hazard ingredient.Read moreShow less
EWG 5–6 Skin conditioning

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinal)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinal

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

ASCORBIC ACID

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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