1% Salicylic Acid 1% Azelaic Acid 1% Niacinamide

Isomers Skincare Laboratories

Where to buy Possibly in stock

About this product

The Isomers Skincare Laboratories 1% Salicylic Acid 1% Azelaic Acid 1% Niacinamide is a serums, essence, ampoule. Our analysis of its 12 ingredients (11 low-risk) rates it Excellent (96/100). Based on its ingredients, it looks well-suited to oily / acne-prone skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
12
Low-risk
11
Fragrance
Fragrance-free
Origin
Canada

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe Minimal Ingredients

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 3/4
Good for dry skin
Butylene Glycol Glycerin Camellia Sinensis Leaf Extract
Caution for dry skin
Glycerin Salicylic Acid Camellia Sinensis Leaf Extract Polysorbate 20
Oily/Acne-Prone Skin 3/0
Good for oily/acne-prone skin
Azelaic Acid Salicylic Acid Camellia Sinensis Leaf Extract
Sensitive Skin 3/5
Good for sensitive skin
Glycerin Hydroxyacetophenone Camellia Sinensis Leaf Extract
Caution for sensitive skin
Azelaic Acid Butylene Glycol Glycerin Salicylic Acid Camellia Sinensis Leaf Extract

Ingredients list

12 total
Lower hazard (1) Higher hazard (4)
All12 Skin Conditioning6 Solvent5 Masking4 Fragrance4 Humectant4 Hair Conditioning3 Antioxidant2 Skin Protecting2
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
Propanediol
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
1
A
Azelaic Acid
(Fragrance, Ph Adjuster, Buffering Agent, Masking)
4
B
Salicylic Acid
(Antiacne Agent, Antidandruff Agent, Corn/Callus/Wart Remover, Denaturant, Exfoliant, Fragrance, Hair Conditioning, Skin Conditioning, Keratolytic, Masking, Preservative)
Good for Oily Skin
Good for Oily Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
1
B
Camellia Sinensis Leaf Extract
(Antimicrobial, Antioxidant, Astringent, Emollient, Humectant, Masking, Oral Care Agent, Skin Conditioning, Skin Protecting, Tonic, Uv Absorber)
Good for Oily Skin
Good for Oily Skin
1
Hydroxyacetophenone
(Antioxidant)
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
Tetrahydroxypropyl Ethylenediamine
(Chelating Agent)
1
A
1,2-Hexanediol
(Solvent)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Antioxidants
Shields skin from free radical damage.
BHA
Unclogs pores and reduces excess oil.
Niacinamide
Strengthens, smooths, and brightens skin.
Azelaic Acid
Gently exfoliates and reduces inflammation.

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
BrighteningRestores radiance to dull, tired skin.
Reduces IrritationEases discomfort and supports skin resilience.
Good For Oily SkinBalances oil and helps reduce shine.
Reduces Large PoresMinimizes the look of enlarged pores.
Redness ReducingSoothes visible redness and calms irritation.
Barrier RepairStrengthen and restore your skin's natural barrier.
Acne FightingFights acne and helps prevent breakouts.

Concerns

Not fungal acne (malassezia) safe
May not suit dry skin
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Propanediol
Solvent, Viscosity decreasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 SolventViscosity decreasing agentViscosity controlling
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Azelaic Acid
Fragrance, Ph adjuster
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragrancePh adjusterBuffering agentMasking
Hydroxyacetophenone
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 Antioxidant
Tetrahydroxypropyl Ethylenediamine
Chelating agent
Low-hazard ingredient.Read moreShow less
EWG 1 Chelating agent
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Salicylic Acid
Antiacne agent, Antidandruff agent
Skin irritation can occur at high concentrationRead moreShow less
EWG 4 CIR B Antiacne agentAntidandruff agentCorn/callus/wart removerDenaturantExfoliantFragranceHair conditioningSkin conditioningKeratolyticMaskingPreservative Good for Oily SkinBad for Sensitive Skin
Camellia Sinensis Leaf Extract
Antimicrobial, Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B AntimicrobialAntioxidantAstringentEmollientHumectantMaskingOral care agentSkin conditioningSkin protectingTonicUv absorber Good for Oily Skin
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Morning only: Apply as the last step of your AM routine, after moisturiser, and reapply every ~2 hours of sun exposure.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Use with caution
BHA (salicylic) (Salicylic Acid)

Low-strength topical salicylic acid (BHA) is generally considered fine. Caution is usually reserved for high-strength leave-on products and salicylic peels.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

BHA (salicylic) 0.5–2%

Salicylic acid is OTC-capped at 2%; 0.5–2% is the usual leave-on range. Much below that it acts more as a soothing agent than an exfoliant.

Salicylic Acid

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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