Retiniacin Night Renewing Treatment Serum

Isomers Skincare Laboratories

Where to buy Possibly in stock

About this product

The Isomers Skincare Laboratories Retiniacin Night Renewing Treatment Serum is a serums, essence, ampoule. Our analysis of its 17 ingredients (10 low-risk) rates it Excellent (88/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
17
Low-risk
10
Fragrance
Fragrance-free
Origin
Canada

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 3/2
Good for dry skin
Caprylic/Capric Triglyceride Glycerin Propylene Glycol
Caution for dry skin
Xanthan Gum Glycerin
Oily/Acne-Prone Skin 1/0
Good for oily/acne-prone skin
Retinol
Sensitive Skin 3/5
Good for sensitive skin
Sodium Ascorbate Glycerin Hydroxyacetophenone
Caution for sensitive skin
Caprylic/Capric Triglyceride Glycerin Propylene Glycol Retinol Retinyl Acetate

Ingredients list

17 total
Lower hazard (1) Higher hazard (9)
All17 Skin Conditioning12 Solvent5 Humectant4 Fragrance4 Emulsion Stabilising3 Antioxidant3 Viscosity Controlling2 Viscosity Decreasing Agent2
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
Carthamus Tinctorius Oleosomes
(Emulsion Stabilising, Skin Conditioning, Skin Conditioning Emollient)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
9
Retinyl Acetate
(Skin Conditioning)
Retinyl Palmitate
(Skin Conditioning, Skin Conditioning Miscellaneous)
1
Melothria Heterophylla Root Extract
(Skin Conditioning)
sh-Oligopeptide-1
(Skin Conditioning)
1
Hydroxyacetophenone
(Antioxidant)
3
B
Propylene Glycol
(Fragrance, Humectant, Skin Conditioningagent Miscellaneous, Solvent, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
1,2-Hexanediol
(Solvent)
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
SANTALUM ALBUM OIL
(Fragrance)
1
A
Sodium Ascorbate
(Antioxidant)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Retinoid
Visibly reduces the signs of aging.
Antioxidants
Shields skin from free radical damage.
Vitamin C
Brightens, evens tone, and supports collagen.
Vitamin E
Protects skin and soothes irritation.
Niacinamide
Strengthens, smooths, and brightens skin.
Peptides
Supports skin hydration and improves firmness.
Show all 6 key ingredients

Benefits

BrighteningRestores radiance to dull, tired skin.
Scar HealingImproves the look of marks and scars.
HydratingBoosts hydration and relieves dry, tight skin.
Dark SpotsFades dark spots for even skin tone.
Anti-AgingSoftens lines and helps skin look youthful.
Redness ReducingSoothes visible redness and calms irritation.
Barrier RepairStrengthen and restore your skin's natural barrier.
Reduces Large PoresMinimizes the look of enlarged pores.

Concerns

Not fungal acne (malassezia) safe
Retinol — higher EWG
Retinyl Acetate — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Carthamus Tinctorius Oleosomes
Emulsion stabilising, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Emulsion stabilisingSkin conditioningSkin conditioning emollient
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
TOCOPHEROL
Antioxidant, Fragrance
Limited public safety data.Read moreShow less
EWG N/A AntioxidantFragranceSkin conditioning
Retinyl Palmitate
Skin conditioning, Skin conditioning miscellaneous
Limited public safety data.Read moreShow less
EWG N/A Skin conditioningSkin conditioning miscellaneous
Melothria Heterophylla Root Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
sh-Oligopeptide-1
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Hydroxyacetophenone
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 Antioxidant
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Xanthan Gum
Binding agent, Emulsion stabilising
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Binding agentEmulsion stabilisingSkin conditioningSurfactant -emulsifying agentViscosity increasing agentBindingGel formingViscosity controlling
SANTALUM ALBUM OIL
Fragrance
Limited public safety data.Read moreShow less
EWG N/A Fragrance
Sodium Ascorbate
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antioxidant
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Retinyl Acetate
Skin conditioning
Higher-hazard ingredient.Read moreShow less
EWG 9 Skin conditioning
Propylene Glycol
Fragrance, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B FragranceHumectantSkin-conditioningagent - miscellaneousSolventViscosity decreasing agentSkin conditioningViscosity controlling Good for Dry Skin
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol, Retinyl Acetate, Retinyl Palmitate)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol, Retinyl Acetate, Retinyl Palmitate

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

Sodium Ascorbate

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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