Vitamin C12 Serum
The La Roche-Posay Vitamin C12 Serum is a serums, essence, ampoule. Our analysis of its 30 ingredients (24 low-risk) rates it Excellent (96/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.
The La Roche-Posay Vitamin C12 Serum is a serums, essence, ampoule. Our analysis of its 30 ingredients (24 low-risk) rates it Excellent (96/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.
Summarised from our ingredient analysis — not brand marketing copy.
The evidence
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
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Water
(Solvent) |
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ASCORBIC ACID
(Antioxidant, Buffering, Fragrance, Skin Conditioning) |
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Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning) |
Silicone
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Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent) |
Good for Dry Skin
Fungal Acne Trigger
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Alcohol Denat.
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling) |
Bad for Dry Skin
Bad for Sensitive Skin
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Potassium Hydroxide
(Ph Adjuster, Buffering Agent) |
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Polysilicone-11
(Film Forming) |
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Silica
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Opacifying, Viscosity Controlling) |
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Pentaerythrityl Tetraethylhexanoate
(Binding Agent, Skin Conditioning Agent Occlusive, Viscosity Increasing Agent, Emollient, Viscosity Controlling) |
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PEG-20 Methyl Glucose Sesquistearate
(Skin Conditioning, Emollient, Emulsifying, Surfactant) |
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Sodium Hyaluronate
(Skin Conditioning, Humectant) |
Good for Dry Skin
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Adenosine
(Skin Conditioning) |
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Poloxamer 338
(Emulsifying, Surfactant) |
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Ammonium Polyacryloyldimethyl Taurate
(Emulsion Stabilising, Viscosity Increasing Agent, Viscosity Controlling) |
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Hydrolyzed Hyaluronic Acid
(Hair Conditioning, Humectant, Skin Conditioning) |
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Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent) |
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Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant) |
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Citric Acid
(Chelating Agent, Fragrance, Ph Adjuster, Buffering Agent, Masking) |
Bad for Sensitive Skin
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Laureth-7
(Emulsifying, Surfactant) |
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Trisodium Ethylenediamine Disuccinate
(Chelating Agent) |
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Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone
(Emollient, Emulsifying, Skin Conditioning, Surfactant) |
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Acetyl Dipeptide-1 Cetyl Ester
(Hair Conditioning, Skin Conditioning) |
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Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling) |
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Pentylene Glycol
(Skin Conditioning, Solvent) |
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Polyacrylamide
(Binding Agent, Film Forming, Hair Fixing, Antistatic Agent, Binding) |
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C13-14 Isoparaffin
(Emollient, Solvent) |
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TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning) |
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Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
(Antioxidant) |
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Salicylic Acid
(Antiacne Agent, Antidandruff Agent, Corn/Callus/Wart Remover, Denaturant, Exfoliant, Fragrance, Hair Conditioning, Skin Conditioning, Keratolytic, Masking, Preservative) |
Good for Oily Skin
Bad for Sensitive Skin
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PARFUM
(Fragrance, Perfuming) |
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How to use
General guidance from this product's category and active ingredients — always follow the directions on the package.
Trust & honesty
Contains ingredients some choose to avoid or double-check while pregnant or nursing.
Low-strength topical salicylic acid (BHA) is generally considered fine. Caution is usually reserved for high-strength leave-on products and salicylic peels.
This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.
The concentrations these actives are typically effective at in research — not a measurement of this product.
L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.
ASCORBIC ACID
Salicylic acid is OTC-capped at 2%; 0.5–2% is the usual leave-on range. Much below that it acts more as a soothing agent than an exfoliant.
Salicylic Acid
INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.
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