Spicule Retinol PDRN Cream

Mary & May

Where to buy Possibly in stock

About this product

The Mary & May Spicule Retinol PDRN Cream is a moisturizer. Our analysis of its 52 ingredients (44 low-risk) rates it Excellent (98/100). Based on its ingredients, it looks well-suited to oily / acne-prone skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Moisturizers
Ingredients
52
Low-risk
44
Fragrance
Fragrance-free
Origin
South Korea

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 9/13
Good for dry skin
Glyceryl Stearate Glyceryl Acrylate/Acrylic Acid Copolymer Macadamia Ternifolia Seed Oil Cetyl Ethylhexanoate Oleic Acid Caprylic/Capric Triglyceride Sodium Hyaluronate Glycerin Cholesterol
Caution for dry skin
C12-20 Alkyl Glucoside Dextrin Lauryl Glucoside Myristyl Glucoside Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Sorbitan Oleate Stearic Acid Oleic Acid Xanthan Gum Caprylyl/Capryl Glucoside Glycerin Polyglyceryl-10 Laurate Hydrogenated Lecithin
Oily/Acne-Prone Skin 1/0
Good for oily/acne-prone skin
Retinol
Sensitive Skin 3/7
Good for sensitive skin
Glycerin Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate Allantoin
Caution for sensitive skin
Sorbitan Oleate Stearic Acid Arginine Oleic Acid Caprylic/Capric Triglyceride Glycerin Retinol

Ingredients list

52 total
Lower hazard (1) Higher hazard (9)
All52 Skin Conditioning36 Viscosity Controlling11 Emulsifying9 Emulsion Stabilising9 Fragrance7 Surfactant6 Film Forming6 Emollient6
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
Methylpropanediol
(Solvent)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
1,2-Hexanediol
(Solvent)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
1
A
Panthenol
(Antistatic Agent, Hair Conditioning, Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
1
Polypropylsilsesquioxane
(Binding Agent, Film Forming)
1
C14-22 Alcohols
(Emulsion Stabilising)
1
Ammonium Acryloyldimethyltaurate/VP Copolymer
(Viscosity Controlling)
1
A
Glyceryl Stearate
(Emollient, Emulsifying)
Fungal Acne
Fungal Acne Trigger
1
B
Cetyl Ethylhexanoate
(Skin Conditioning, Emollient)
Vinyldimethicone
(Viscosity Controlling)
1
Macadamia Ternifolia Seed Oil
(Emollient)
Brassica Campestris Sterols
(Skin Conditioning, Skin Conditioning Emollient)
1
B
Polyglyceryl-10 Laurate
(Skin Conditioning, Emulsifying, Surfactant)
1
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
(Emulsion Stabilising, Film Forming, Viscosity Controlling)
1
B
C12-20 Alkyl Glucoside
(Emulsifying, Surfactant)
1
A
Arginine
(Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Masking)
1
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
(Skin Conditioning)
1
A
Cholesterol
(Emulsion Stabilising, Skin Conditioning, Viscosity Increasing Agent, Emollient, Emulsifying, Stabilising, Viscosity Controlling)
1
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
(Anticaking Agent, Emulsion Stabilising, Opacifying, Suspending Agent Nonsurfactant, Viscosity Increasing Agent)
Hydrolyzed Sponge
(Skin Conditioning)
1
A
Polyisobutene
(Binding Agent, Film Forming, Viscosity Increasing Agent, Binding, Viscosity Controlling)
1
Gardenia Florida Fruit Extract
(Skin Conditioning)
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
1
A
Allantoin
(Skin Conditioning, Skin Protecting, Soothing)
Good for Oily Skin
Good for Oily Skin
Good for Sensitive Skin
Good for Sensitive Skin
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
Butyrospermum Parkii Butter
(Skin Conditioning, Viscosity Controlling)
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
2
A
Hydrogenated Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Suspending Agent Nonsurfactant)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
1
A
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
(Antioxidant)
1
Adenosine
(Skin Conditioning)
1
A
Dextrin
(Absorbent, Binding Agent, Bulking Agent, Viscosity Increasing Agent, Binding, Viscosity Controlling)
Helianthus Annuus Seed Oil
(Fragrance, Skin Conditioning, Skin Conditioning Emollient)
1
B
Lauryl Glucoside
(Cleansing, Surfactant)
1
Polyglutamic Acid
(Skin Conditioning)
Polyglyceryl-6 Laurate
(Emulsifying)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
1
Ceramide NP
(Hair Conditioning, Skin Conditioning)
1
Caprylyl/Capryl Glucoside
(Cleansing, Foaming, Surfactant)
1
A
Sorbitan Oleate
(Fragrance, Emulsifying, Surfactant)
Bad for Oily Skin
Bad for Oily Skin
Fungal Acne
Fungal Acne Trigger
1
B
Myristyl Glucoside
(Cleansing)
1
A
Stearic Acid
(Fragrance, Sufactant, Emulsifying, Surfactantsurfactant Cleansing Agent Is Included As A Function For The Soap Form Of Stearic Acid., Emulsion Stabilising, Masking, Refatting)
Bad for Oily Skin
Bad for Oily Skin
Fungal Acne
Fungal Acne Trigger
1
Benzotriazolyl Dodecyl p-Cresol
(Uv Absorber)
1
Glyceryl Acrylate/Acrylic Acid Copolymer
(Humectant, Viscosity Controlling)
1
A
Oleic Acid
(Fragrance, Sufactantsurfactant Cleansing Agent Is Included As A Function For The Soap Form Of Oleic Acid., Emollient, Emulsifying)
Fungal Acne
Fungal Acne Trigger
1
A
PVM/MA Copolymer
(Antistatic Agent, Binding, Emulsion Stabilising, Film Forming, Hair Fixing, Viscosity Controlling)
2
Beta-Carotene
(Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
1
Sodium DNA
(Skin Conditioning)

My Ingredient Notes

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Key ingredients

Glycerin
Humectant, Skin Protecting
Niacinamide
Skin Conditioning
Panthenol
Skin Conditioning
Caprylic/Capric Triglyceride
Emollient, Skin Conditioning
Glyceryl Stearate
Emollient
Cetyl Ethylhexanoate
Skin Conditioning, Emollient

Benefits

Good for oily/acne-prone skin

Concerns

Not fungal acne (malassezia) safe
Retinol — higher EWG
May not suit dry skin
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Methylpropanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
Polypropylsilsesquioxane
Binding agent, Film forming
Low-hazard ingredient.Read moreShow less
EWG 1 Binding agentFilm forming
C14-22 Alcohols
Emulsion stabilising
Low-hazard ingredient.Read moreShow less
EWG 1 Emulsion stabilising
Ammonium Acryloyldimethyltaurate/VP Copolymer
Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 Viscosity controlling
Cetyl Ethylhexanoate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioningEmollient
Vinyldimethicone
Viscosity controlling
Limited public safety data.Read moreShow less
EWG N/A Viscosity controlling
Macadamia Ternifolia Seed Oil
Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 Emollient
Brassica Campestris Sterols
Skin conditioning, Skin conditioning emollient
Limited public safety data.Read moreShow less
EWG N/A Skin conditioningSkin conditioning emollient
Polyglyceryl-10 Laurate
Skin conditioning, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioningEmulsifyingSurfactant
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion stabilising, Film forming
Low-hazard ingredient.Read moreShow less
EWG 1 Emulsion stabilisingFilm formingViscosity controlling
C12-20 Alkyl Glucoside
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B EmulsifyingSurfactant
+ 27 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Panthenol
Antistatic agent, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antistatic agentHair conditioningSkin conditioning Good for Dry Skin
Glyceryl Stearate
Emollient, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientEmulsifying Fungal-acne trigger
Allantoin
Skin conditioning, Skin protecting
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningSkin protectingSoothing Good for Oily SkinGood for Sensitive Skin
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Sorbitan Oleate
Fragrance, Emulsifying
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR A FragranceEmulsifyingSurfactant Bad for Oily SkinFungal-acne trigger
Stearic Acid
Fragrance, Sufactant
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR A FragranceSufactantEmulsifyingSurfactantsurfactant-cleansing agent is included as a function for the soap form of stearic acid.Emulsion stabilisingMaskingRefatting Bad for Oily SkinFungal-acne trigger
Oleic Acid
Fragrance, Sufactantsurfactant-cleansing agent is included as a function for the soap form of oleic acid.
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSufactantsurfactant-cleansing agent is included as a function for the soap form of oleic acid.EmollientEmulsifying Fungal-acne trigger
Beta-Carotene
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 2 Skin conditioning Good for Dry Skin

How to use

How to use

  • 1 Where it fits: Apply near the end of your routine, after thinner serums.
  • 2 Morning only: Apply as the last step of your AM routine, after moisturiser, and reapply every ~2 hours of sun exposure.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Officially notified as a cosmetic in Malaysia (NPRA). Government registration record.

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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