One Day Zero Exosome Shot

MediCube

Where to buy Possibly in stock

About this product

The MediCube One Day Zero Exosome Shot is a serums, essence, ampoule. Our analysis of its 27 ingredients (22 low-risk) rates it Excellent (100/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
27
Low-risk
22
Fragrance
Fragrance-free
Origin
South Korea

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 7/5
Good for dry skin
Pueraria Lobata Root Extract Gluconolactone Ethylhexyl Palmitate Butylene Glycol Glycerin Hydrogenated Polydecene Sodium Polyacrylate
Caution for dry skin
C12-14 Pareth-12 Caprylyl/Capryl Glucoside Calcium Silicate Glycerin Sodium Polyacrylate
Oily/Acne-Prone Skin 1/0
Good for oily/acne-prone skin
Betaine Salicylate
Sensitive Skin 2/7
Good for sensitive skin
Glycerin Campsis Grandiflora Flower Extract
Caution for sensitive skin
Gluconolactone Dipropylene Glycol Ethylhexyl Palmitate Butylene Glycol Glycerin Citric Acid Hydrogenated Polydecene

Ingredients list

27 total
Lower hazard (1) Higher hazard (3)
All27 Skin Conditioning16 Solvent7 Fragrance7 Hair Conditioning5 Humectant5 Viscosity Controlling4 Masking3 Chelating Agent2
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
A
Dipropylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Masking, Viscosity Controlling)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
A
1,2-Hexanediol
(Solvent)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
3
B
Sodium Polyacrylate
(Absorbent, Emulsion Stabilising, Film Forming, Hair Fixing, Skin Conditioning Agent Emollient, Viscosity Controlling Agent, Viscosity Increasing Agent, Binding, Skin Conditioning)
1
B
Ethylhexyl Palmitate
(Fragrance, Skin Conditioning, Emollient, Perfuming)
Fungal Acne
Fungal Acne Trigger
Hydrolyzed Sponge
(Skin Conditioning)
1
B
C12-14 Pareth-12
(Emulsifying, Surfactant)
2
A
Hydrogenated Polydecene
(Fragrance, Hair Conditioning, Skin Conditioning, Emollient, Solvent)
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
1
Adenosine
(Skin Conditioning)
1
Caprylyl/Capryl Glucoside
(Cleansing, Foaming, Surfactant)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
1
A
Panthenol
(Antistatic Agent, Hair Conditioning, Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
1
A
Calcium Silicate
(Absorbent, Bulking Agent, Opacifying, Pearlescent, Viscosity Controlling)
Lactobacillus Extracellular Vesicles
(Hair Conditioning, Skin Conditioning)
Campsis Grandiflora Flower Extract
(Antioxidant, Skin Conditioning)
1
Pueraria Lobata Root Extract
(Humectant)
2
Pinus Palustris Leaf Extract
(Tonic)
Oenothera Biennis Flower Extract
(Astringent)
Ulmus Davidiana Root Extract
(Skin Conditioning)
3
Sodium Silicate
(Buffering Agent, Anticorrosive, Ph Adjuster)
1
Betaine Salicylate
(Antimicrobial Agent, Exfoliant, Keratolytic)
2
A
Citric Acid
(Chelating Agent, Fragrance, Ph Adjuster, Buffering Agent, Masking)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
Gluconolactone
(Fragrance, Humectant, Solvent)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Glycerin
Humectant, Skin Protecting
Butylene Glycol
Skin Conditioning, Humectant
Niacinamide
Skin Conditioning
Sodium Polyacrylate
Skin Conditioning
Ethylhexyl Palmitate
Skin Conditioning, Emollient
Hydrolyzed Sponge
Skin Conditioning

Benefits

Good for dry skin
Good for oily/acne-prone skin

Concerns

Not fungal acne (malassezia) safe
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Dipropylene Glycol
Fragrance, Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSolventViscosity decreasing agentMaskingViscosity controlling
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Sodium Polyacrylate
Absorbent, Emulsion stabilising
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B AbsorbentEmulsion stabilisingFilm formingHair fixingSkin-conditioning agent -emollientViscosity controlling agentViscosity increasing agentBindingSkin conditioning
Hydrolyzed Sponge
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
C12-14 Pareth-12
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B EmulsifyingSurfactant
Hydrogenated Polydecene
Fragrance, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A FragranceHair conditioningSkin conditioningEmollientSolvent
Ethylhexylglycerin
Deodorant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A DeodorantSkin conditioning
Adenosine
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Caprylyl/Capryl Glucoside
Cleansing, Foaming
Low-hazard ingredient.Read moreShow less
EWG 1 CleansingFoamingSurfactant
Disodium EDTA
Chelating agent, Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Chelating agentViscosity controlling
Calcium Silicate
Absorbent, Bulking agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A AbsorbentBulking agentOpacifyingPearlescentViscosity controlling
Lactobacillus Extracellular Vesicles
Hair conditioning, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Hair conditioningSkin conditioning
Campsis Grandiflora Flower Extract
Antioxidant, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A AntioxidantSkin conditioning
+ 7 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Ethylhexyl Palmitate
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B FragranceSkin conditioningEmollientPerfuming Fungal-acne trigger
Panthenol
Antistatic agent, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antistatic agentHair conditioningSkin conditioning Good for Dry Skin
Citric Acid
Chelating agent, Fragrance
Skin irritation can occur at high concentrationRead moreShow less
EWG 2 CIR A Chelating agentFragrancePh adjusterBuffering agentMasking Bad for Sensitive Skin

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening, start slow: Best in the PM a few times a week to begin with; avoid layering with other strong actives the same night.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Use with caution
BHA (salicylic) (Betaine Salicylate)

Low-strength topical salicylic acid (BHA) is generally considered fine. Caution is usually reserved for high-strength leave-on products and salicylic peels.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

BHA (salicylic) 0.5–2%

Salicylic acid is OTC-capped at 2%; 0.5–2% is the usual leave-on range. Much below that it acts more as a soothing agent than an exfoliant.

Betaine Salicylate

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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