Retinol Synergist

Mother Science

Where to buy Possibly in stock

About this product

The Mother Science Retinol Synergist is a serums, essence, ampoule. Our analysis of its 33 ingredients (27 low-risk) rates it Excellent (96/100). Based on its ingredients, it looks well-suited to oily / acne-prone skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
33
Low-risk
27
Fragrance
Fragrance-free
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 7/10
Good for dry skin
Dicaprylyl Carbonate Cetearyl Alcohol Cetyl Palmitate Caprylic/Capric Triglyceride Glycerin Cholesterol Trehalose
Caution for dry skin
Sodium Lauroyl Lactylate Sorbitan Olivate Sorbitan Isostearate Xanthan Gum Glycerin Laureth-23 Sodium Hydroxide Polysorbate 20 Polysorbate 60 Trideceth-6 Phosphate
Oily/Acne-Prone Skin 1/0
Good for oily/acne-prone skin
Retinol
Sensitive Skin 2/5
Good for sensitive skin
Glycerin Hydroxyacetophenone
Caution for sensitive skin
Cetyl Palmitate Caprylic/Capric Triglyceride Glycerin Phenoxyethanol Retinol

Ingredients list

33 total
Lower hazard (1) Higher hazard (9)
All33 Skin Conditioning18 Emulsifying9 Emulsion Stabilising8 Surfactant7 Viscosity Controlling6 Hair Conditioning6 Emollient5 Solvent5
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
Dimethyl Isosorbide
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1
Dicaprylyl Carbonate
(Skin Conditioning, Emollient)
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Cetearyl Alcohol
(Emulsion Stabilising, Opacifying, Foam Boosting, Viscosity Increasingagent Aqueous, Viscosity Increasing Agent, Emollient, Emulsifying, Viscosity Controlling)
1
A
1,2-Hexanediol
(Solvent)
1
B
Cetearyl Olivate
(Hair Conditioning)
1
A
Sorbitan Olivate
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Trehalose
(Flavoring Agent, Humectant, Moisturising)
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
1
Ceramide NP
(Hair Conditioning, Skin Conditioning)
Ceramide AP
(Hair Conditioning, Skin Conditioning)
Ceramide EOP
(Hair Conditioning, Skin Conditioning)
1
Phytosphingosine
(Hair Conditioning, Skin Conditioning)
1
A
Cholesterol
(Emulsion Stabilising, Skin Conditioning, Viscosity Increasing Agent, Emollient, Emulsifying, Stabilising, Viscosity Controlling)
1
Sodium Lauroyl Lactylate
(Emulsifying, Surfactant)
1
Dunaliella Salina Extract
(Skin Conditioning)
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
1
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
(Emulsion Stabilising, Viscosity Controlling)
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
B
Cetyl Palmitate
(Fragrance, Emollient, Masking, Skin Conditioning)
3
B
Polysorbate 60
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
A
Sorbitan Isostearate
(Emulsifying, Surfactant)
3
B
Laureth-23
(Cleansing, Emulsifying, Surfactant)
Bad for Oily Skin
Bad for Oily Skin
Trideceth-6 Phosphate
(Emulsifying, Surfactant)
1
Tetrasodium Glutamate Diacetate
(Chelating Agent)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
3
B
Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent)
1
Hydroxyacetophenone
(Antioxidant)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Dicaprylyl Carbonate
Skin Conditioning, Emollient
Caprylic/Capric Triglyceride
Emollient, Skin Conditioning
Glycerin
Humectant, Skin Protecting
Cetearyl Alcohol
Emollient
Retinol
Skin Conditioning
Trehalose
Humectant, Moisturising

Benefits

Good for oily/acne-prone skin

Concerns

Contains paraben
Not fungal acne (malassezia) safe
Retinol — higher EWG
May not suit dry skin
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Dimethyl Isosorbide
Solvent, Viscosity decreasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 SolventViscosity decreasing agentViscosity controlling
Dicaprylyl Carbonate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioningEmollient
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
Cetearyl Alcohol
Emulsion stabilising, Opacifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingOpacifyingFoam boostingViscosity increasingagent - aqueousViscosity increasing agentEmollientEmulsifyingViscosity controlling
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Cetearyl Olivate
Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Hair conditioning
Trehalose
Flavoring agent, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Flavoring agentHumectantMoisturising
TOCOPHEROL
Antioxidant, Fragrance
Limited public safety data.Read moreShow less
EWG N/A AntioxidantFragranceSkin conditioning
Ceramide NP
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Hair conditioningSkin conditioning
Ceramide AP
Hair conditioning, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Hair conditioningSkin conditioning
Ceramide EOP
Hair conditioning, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Hair conditioningSkin conditioning
Phytosphingosine
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Hair conditioningSkin conditioning
Cholesterol
Emulsion stabilising, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingSkin conditioningViscosity increasing agentEmollientEmulsifyingStabilisingViscosity controlling
Sodium Lauroyl Lactylate
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 EmulsifyingSurfactant
+ 11 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Sorbitan Olivate
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmulsifyingSurfactant Fungal-acne trigger
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Polysorbate 60
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Laureth-23
Cleansing, Emulsifying
Potentially comedogenic - can block poresRead moreShow less
EWG 3 CIR B CleansingEmulsifyingSurfactant Bad for Oily Skin
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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