Renew MD Advanced Retinal Serum

Osmosis Beauty

Where to buy Possibly in stock

About this product

The Osmosis Beauty Renew MD Advanced Retinal Serum is a serums, essence, ampoule. Our analysis of its 37 ingredients (25 low-risk) rates it Excellent (95/100). Based on its ingredients, it looks well-suited to oily / acne-prone skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
37
Low-risk
25
Fragrance
Fragrance-free
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 4/8
Good for dry skin
Ectoin Sodium Hyaluronate Glycerin Lactic Acid
Caution for dry skin
Cyclodextrin Xanthan Gum Glycerin Phosphatidylcholine Hydroxyproline Alcohol Sodium Hydroxide Alcohol Denat.
Oily/Acne-Prone Skin 2/0
Good for oily/acne-prone skin
Alcohol Alcohol Denat.
Sensitive Skin 4/11
Good for sensitive skin
Asiaticoside Caprooyl Tetrapeptide-3 Glycerin Thioctic Acid
Caution for sensitive skin
Santalum Austrocaledonicum Wood Oil Asiaticoside Glycerin Hydroxypropyl Cyclodextrin Citric Acid Alcohol Potassium Sorbate Lactic Acid Alcohol Denat. Benzyl Alcohol Pogostemon Cablin Leaf Oil

Ingredients list

37 total
Lower hazard (1) Higher hazard (6)
All37 Skin Conditioning30 Solvent7 Masking7 Fragrance6 Viscosity Controlling5 Hair Conditioning4 Humectant4 Buffering Agent4
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
1
A
Phosphatidylcholine
(Skin Conditioning, Emulsifying, Surfactant)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Pentylene Glycol
(Skin Conditioning, Solvent)
1
A
Cyclodextrin
(Absorbent, Chelating Agent)
1
Asiaticoside
(Antioxidant, Skin Conditioning, Perfuming)
1
Palmitoyl Tripeptide-38
(Skin Conditioning)
Dipeptide-6
(Skin Conditioning)
5
6
Retinal
(Skin Conditioning)
1
Ectoin
(Buffering Agent, Skin Conditioning, Emollient)
1
Caprooyl Tetrapeptide-3
(Skin Protecting)
2
Thioctic Acid
(Antioxidant)
1
Chlorella Vulgaris Extract
(Skin Conditioning)
Epilobium Angustifolium Flower/Leaf/Stem Extract
(Skin Conditioning)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
4
B
Lactic Acid
(Exfoliant, Fragrance, Humectant, Ph Adjuster, Skin Conditioning Agent Humectant, Skin Conditioning, Buffering Agent)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Beta-Glucan
(Bulking Agent, Skin Conditioning)
Fulvic Acid
(Skin Conditioning)
1
Hydroxyproline
(Hair Conditioning, Skin Conditioning, Antistatic Agent, Surfactant)
1
Santalum Austrocaledonicum Wood Oil
(Flavoring Agent, Masking, Perfuming)
1
A
Rubus Chamaemorus Seed Oil
(Skin Conditioning)
Hamamelis Virginiana Water
(Astringent, Hair Conditioning, Skin Conditioning, Soothing)
1
Dimethyl Sulfone
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
Pogostemon Cablin Leaf Oil
(Masking)
lavandula angustifolia oil
(Fragrance, Tonic)
Lonicera Caprifolium Flower Extract
(Perfuming, Skin Conditioning)
Lonicera Japonica Flower Extract
(Skin Conditioning)
1
A
Dextran
(Binding Agent, Bulking Agent, Binding, Viscosity Controlling)
1
A
Hydroxypropyl Cyclodextrin
(Chelating Agent, Emulsion Stabilising, Masking, Skin Conditioning)
4
Alcohol Denat.
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
2
A
Citric Acid
(Chelating Agent, Fragrance, Ph Adjuster, Buffering Agent, Masking)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
3
B
Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent)
2
Alcohol
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
3
A
Potassium Sorbate
(Fragrance, Preservative)
5
A
Benzyl Alcohol
(External Analgesic, Fragrance, Oral Health Care Drug, Preservative, Solvent, Viscosity Decreasing Agent, Masking)
Allergens
Allergens

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Niacinamide
Skin Conditioning
Phosphatidylcholine
Skin Conditioning
Glycerin
Humectant, Skin Protecting
Pentylene Glycol
Skin Conditioning
Asiaticoside
Antioxidant, Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning

Benefits

Good for oily/acne-prone skin

Concerns

Contains eu allergen
Not fungal acne (malassezia) safe
May not suit dry skin
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Phosphatidylcholine
Skin conditioning, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningEmulsifyingSurfactant
Pentylene Glycol
Skin conditioning, Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningSolvent
Cyclodextrin
Absorbent, Chelating agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A AbsorbentChelating agent
Asiaticoside
Antioxidant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 AntioxidantSkin conditioningPerfuming
Palmitoyl Tripeptide-38
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Dipeptide-6
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Ectoin
Buffering agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Buffering agentSkin conditioningEmollient
Caprooyl Tetrapeptide-3
Skin protecting
Low-hazard ingredient.Read moreShow less
EWG 1 Skin protecting
Thioctic Acid
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 2 Antioxidant
Chlorella Vulgaris Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Epilobium Angustifolium Flower/Leaf/Stem Extract
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Beta-Glucan
Bulking agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Bulking agentSkin conditioning
Fulvic Acid
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
+ 14 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Retinal
Skin conditioning
Moderate-hazard ingredient.Read moreShow less
EWG 5–6 Skin conditioning
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Lactic Acid
Exfoliant, Fragrance
Skin irritation can occur at high concentrationRead moreShow less
EWG 4 CIR B ExfoliantFragranceHumectantPh adjusterSkin-conditioning agent -humectantSkin conditioningBuffering agent Bad for Sensitive Skin
Alcohol Denat.
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 4 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
Citric Acid
Chelating agent, Fragrance
Skin irritation can occur at high concentrationRead moreShow less
EWG 2 CIR A Chelating agentFragrancePh adjusterBuffering agentMasking Bad for Sensitive Skin
Alcohol
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 2 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
Benzyl Alcohol
External analgesic, Fragrance
Moderate-hazard ingredient.Read moreShow less
EWG 5 CIR A External analgesicFragranceOral health care drugPreservativeSolventViscosity decreasing agentMasking Allergens

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinal)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinal

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

AHA (acid exfoliant) 5–10% (OTC)

OTC leave-on AHAs are usually 5–10%. The effect also depends on pH and free-acid value, not the percentage alone.

Lactic Acid

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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