25% Vitamin C + Glutathione Clinical Serum
The Paula's Choice 25% Vitamin C + Glutathione Clinical Serum is a serums, essence, ampoule. Our analysis of its 41 ingredients (34 low-risk) rates it Excellent (99/100). Based on its ingredients, it looks well-suited to dry skin.
The Paula's Choice 25% Vitamin C + Glutathione Clinical Serum is a serums, essence, ampoule. Our analysis of its 41 ingredients (34 low-risk) rates it Excellent (99/100). Based on its ingredients, it looks well-suited to dry skin.
Summarised from our ingredient analysis — not brand marketing copy.
The evidence
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
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Water
(Solvent) |
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Tetrahexyldecyl Ascorbate
(Antioxidant, Skin Conditioning) |
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Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning) |
Silicone
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Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent) |
Good for Dry Skin
Fungal Acne Trigger
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C9-12 Alkane
(Solvent) |
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Ascorbyl Glucoside
(Antioxidant) |
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Silica
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Opacifying, Viscosity Controlling) |
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Pyrus Malus Fruit Extract
(Skin Conditioning) |
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Hydrogenated Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Suspending Agent Nonsurfactant) |
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Polyglyceryl-6 Polyricinoleate
(Skin Conditioning, Emollient, Emulsifying, Surfactant) |
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Acrylates/C10-30 Alkyl Acrylate Crosspolymer
(Emulsion Stabilising, Film Forming, Viscosity Controlling) |
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Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling) |
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Oryza Sativa Bran Extract
(Skin Conditioning, Skin Protecting) |
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Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
(Emulsion Stabilising, Viscosity Controlling) |
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Cetyl Alcohol
(Emulsion Stabilising, Fragrance, Opacifying, Emulsifying, Surfactant, Foam Boosting, Viscosity Increasing Agent, Emollient, Masking, Viscosity Controlling) |
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Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant) |
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Lysine Carboxymethyl Cysteinate
(Skin Conditioning) |
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Coco-Caprylate/Caprate
(Emollient, Skin Conditioning) |
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TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning) |
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Glutathione
(Fragrance, Reducing) |
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Sodium Citrate
(Ph Adjuster, Buffering Agent, Chelating, Masking) |
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Sodium Phytate
(Chelating Agent, Oral Care Agent) |
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Hexylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Emulsifying, Perfuming, Skin Conditioning, Surfactant) |
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Ethylhexylglycerin
(Deodorant, Skin Conditioning) |
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Helianthus Annuus Seed Extract
(Skin Conditioning) |
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Urea
(Buffering Agent, Humectant, Antistatic Agent, Skin Conditioning) |
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Mannitol
(Binding Agent, Flavoring Agent, Humectant, Binding, Masking, Moisturising, Skin Conditioning) |
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Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent) |
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Sodium PCA
(Hair Conditioning, Humectant, Antistatic Agent, Skin Conditioning) |
Good for Dry Skin
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rosmarinus officinalis leaf extract
(Antimicrobial, Fragrance, Skin Conditioning) |
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Polysorbate 60
(Emulsifying, Surfactant) |
Fungal Acne Trigger
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Sorbitan Isostearate
(Emulsifying, Surfactant) |
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Trehalose
(Flavoring Agent, Humectant, Moisturising) |
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ASCORBIC ACID
(Antioxidant, Buffering, Fragrance, Skin Conditioning) |
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Glucose
(Flavoring Agent, Humectant, Skin Conditioning Agent Miscellaneous) |
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Vanilla Planifolia Fruit Extract
(Skin Conditioning, Skin Protecting, Smoothing) |
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Polyquaternium-51
(Film Forming, Humectant, Skin Conditioning) |
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Ergothioneine
(Antioxidant) |
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Triacetin
(Cosmetic Biocide, Fragrance, Plasticizer, Solvent, Antimicrobial, Film Forming, Masking) |
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Sodium Hyaluronate
(Skin Conditioning, Humectant) |
Good for Dry Skin
|
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Phenoxyethanol
(Fragrance, Preservative) |
Paraben
|
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How to use
General guidance from this product's category and active ingredients — always follow the directions on the package.
Trust & honesty
The concentrations these actives are typically effective at in research — not a measurement of this product.
L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.
Tetrahexyldecyl Ascorbate, Ascorbyl Glucoside, ASCORBIC ACID
INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.
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