Paula's Choice RESIST Intensive Wrinkle-Repair Retinol Serum

Paula's Choice

Paula's Choice RESIST Intensive Wrinkle-Repair Retinol Serum

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About this product

The Paula's Choice RESIST Intensive Wrinkle-Repair Retinol Serum is a serums, essence, ampoule. Our analysis of its 21 ingredients (18 low-risk) rates it Excellent (93/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
21
Low-risk
18
Fragrance
Fragrance-free
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 9/2
Good for dry skin
Avena Sativa (Oat) Kernel Extract Neopentyl Glycol Diheptanoate Dimethiconol Dicaprylyl Carbonate Squalane Caprylic/Capric Triglyceride Caprylyl Glycol Cyclopentasiloxane Lecithin
Caution for dry skin
Hexylene Glycol Lecithin
Oily/Acne-Prone Skin 1/0
Good for oily/acne-prone skin
Retinol
Sensitive Skin 3/4
Good for sensitive skin
Avena Sativa (Oat) Kernel Extract Stearyl Glycyrrhetinate Tetrahexyldecyl Ascorbate
Caution for sensitive skin
Caprylic/Capric Triglyceride Hexylene Glycol Phenoxyethanol Retinol

Ingredients list

21 total
Lower hazard (1) Higher hazard (9)
All21 Skin Conditioning26 Emollient9 Hair Conditioning4 Solvent3 Fragrance2 Surfactant2 Emulsifying2 Uv Absorber2
EWG CIR Ingredient Name & Cosmetic Functions Notes
3
A
Cyclopentasiloxane
(Hair Conditioning, Skin Conditioning, Emollient, Solvent)
Silicone
Silicone
1
A
Dimethiconol
(Antifoaming Agent, Skin Conditioning, Emollient, Moisturising)
Silicone
Silicone
1
Neopentyl Glycol Diheptanoate
(Skin Conditioning, Emollient, Viscosity Increasing Agent)
1
Dicaprylyl Carbonate
(Skin Conditioning, Emollient)
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
1
A
Phenyl Trimethicone
(Antifoaming Agent, Hair Conditioning, Skin Conditioning)
Silicone
Silicone
1
A
Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning)
1
(-)-alpha-isabolol
1
Tetrahexyldecyl Ascorbate
(Antioxidant, Skin Conditioning)
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Tocotrienols
(Oral Care Agent, Skin Conditioning, Uv Absorber)
1
Tocopherol (Vitamin E) Good for Dry Skin
Good for Dry Skin
2
3
Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Antistatic Agent, Emollient)
Laminaria Ochroleuca Extract
(Skin Conditioning)
1
B
Avena Sativa (Oat) Kernel Extract
(Antioxidant, Skin Conditioning, Emollient, Abrasive)
1
A
Elaeis Guineensis (Palm) Oil Fungal Acne
Fungal Acne Trigger
1
A
Stearyl Glycyrrhetinate
(Flavoring Agent, Skin Conditioning, Soothing)
1
A
Hexylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Emulsifying, Perfuming, Skin Conditioning, Surfactant)
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Cyclopentasiloxane
Skin Conditioning, Emollient
Dimethiconol
Skin Conditioning, Emollient
Neopentyl Glycol Diheptanoate
Skin Conditioning, Emollient
Dicaprylyl Carbonate
Skin Conditioning, Emollient
Caprylic/Capric Triglyceride
Emollient, Skin Conditioning
Phenyl Trimethicone
Skin Conditioning

Benefits

Good for dry skin
Good for oily/acne-prone skin

Concerns

Contains paraben
Contains silicone
Not fungal acne (malassezia) safe
Retinol — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Neopentyl Glycol Diheptanoate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioningEmollientViscosity increasing agent
Dicaprylyl Carbonate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioningEmollient
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
Squalane
Emollient, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientHair conditioningRefattingSkin conditioning
(-)-alpha-isabolol
Other
Low-hazard ingredient.Read moreShow less
EWG 1
Tetrahexyldecyl Ascorbate
Antioxidant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 AntioxidantSkin conditioning
Tocotrienols
Oral care agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Oral care agentSkin conditioningUv absorber
Lecithin
Skin conditioning, Emulsifying
Low-to-moderate hazard.Read moreShow less
EWG 2–3 Skin conditioningEmulsifyingSurfactantAntistatic agentEmollient
Laminaria Ochroleuca Extract
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Avena Sativa (Oat) Kernel Extract
Antioxidant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B AntioxidantSkin conditioningEmollientAbrasive
Stearyl Glycyrrhetinate
Flavoring agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Flavoring agentSkin conditioningSoothing
Hexylene Glycol
Fragrance, Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSolventViscosity decreasing agentEmulsifyingPerfumingSkin conditioningSurfactant
Caprylyl Glycol
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningEmollientHumectant
Ethylhexylglycerin
Deodorant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A DeodorantSkin conditioning
Cyclopentasiloxane
Hair conditioning, Skin conditioning
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Hair conditioningSkin conditioningEmollientSolvent Silicone
Dimethiconol
Antifoaming agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antifoaming agentSkin conditioningEmollientMoisturising Silicone
Phenyl Trimethicone
Antifoaming agent, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antifoaming agentHair conditioningSkin conditioning Silicone
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Tocopherol (Vitamin E)
Other
Low-hazard ingredient.Read moreShow less
EWG 1 Good for Dry Skin
Elaeis Guineensis (Palm) Oil
Other
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Fungal-acne trigger
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Morning only: Apply as the last step of your AM routine, after moisturiser, and reapply every ~2 hours of sun exposure.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Officially notified as a cosmetic in Malaysia (NPRA). Government registration record.

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

Tetrahexyldecyl Ascorbate

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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