High Potency Intensive Smoothing Serum

Perricone MD

Where to buy Possibly in stock

About this product

The Perricone MD High Potency Intensive Smoothing Serum is a serums, essence, ampoule. Our analysis of its 37 ingredients (31 low-risk) rates it Excellent (98/100). Based on its ingredients, it looks well-suited to dry and sensitive skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
37
Low-risk
31
Fragrance
Fragrance-free
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 15/5
Good for dry skin
Gluconolactone Glyceryl Ricinoleate Glyceryl Stearate Sodium Acetylated Hyaluronate Sodium Hyaluronate Crosspolymer Squalane Caprylyl Glycol Butylene Glycol Sodium Hyaluronate Glycerin Hydrolyzed Glycosaminoglycans Hydrolyzed Hyaluronic Acid Hyaluronic Acid Dimethicone Zinc PCA
Caution for dry skin
Glyceryl Ricinoleate Sorbitan Isostearate Glycerin Polysorbate 20 Polysorbate 60
Oily/Acne-Prone Skin No data
Sensitive Skin 4/4
Good for sensitive skin
Ubiquinone Glycerin Dimethicone Tocopheryl Acetate
Caution for sensitive skin
Gluconolactone Butylene Glycol Glycerin Phenoxyethanol

Ingredients list

37 total
Lower hazard (1) Higher hazard (4)
All37 Skin Conditioning30 Humectant12 Hair Conditioning8 Solvent7 Emulsifying5 Viscosity Controlling5 Emollient5 Surfactant4
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
Diphenylsiloxy Phenyl Trimethicone
(Antifoaming Agent, Hair Conditioning, Skin Conditioning)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone
1
Polymethylsilsesquioxane
(Opacifying)
1
A
Dimethicone/Phenyl Vinyl Dimethicone Crosspolymer
(Viscosity Controlling)
1
A
Glyceryl Stearate
(Emollient, Emulsifying)
Fungal Acne
Fungal Acne Trigger
1
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
(Emulsion Stabilising, Viscosity Controlling)
1
A
Glyceryl Ricinoleate
(Skin Conditioning, Emollient, Emulsifying, Surfactant)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
Dimethyl Isosorbide
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
1
A
Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning)
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
1
Ceramide NP
(Hair Conditioning, Skin Conditioning)
1
Gluconolactone
(Fragrance, Humectant, Solvent)
3
Zinc PCA
(Skin Conditioning, Humectant)
4
Dimethyl MEA
(Ph Adjuster, Buffering Agent)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
3
B
Polysorbate 60
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
A
Sorbitan Isostearate
(Emulsifying, Surfactant)
1
Sodium Hyaluronate Crosspolymer
(Humectant, Skin Conditioning)
olea europaea leaf extract
(Perfuming, Skin Conditioning)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
1
Sodium Acetylated Hyaluronate
(Humectant)
1
Propanediol
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1
A
Hyaluronic Acid
(Skin Conditioning, Viscosity Increasing Agent, Antistatic Agent, Humectant, Moisturising)
1
Hydrolyzed Glycosaminoglycans
(Hair Conditioning, Skin Conditioning, Humectant)
Hydrolyzed Sodium Hyaluronate
(Skin Conditioning)
1
A
1,2-Hexanediol
(Solvent)
1
Ubiquinone
(Antioxidant, Skin Conditioning)
1
Hydrolyzed Hyaluronic Acid
(Hair Conditioning, Humectant, Skin Conditioning)
Acetyl Hexapeptide-38
(Skin Conditioning)
Heptapeptide-6
(Skin Conditioning)
1
Caprylhydroxamic Acid
(Chelating Agent)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Diphenylsiloxy Phenyl Trimethicone
Skin Conditioning
Niacinamide
Skin Conditioning
Dimethicone
Skin Protecting, Emollient
Glyceryl Stearate
Emollient
Glyceryl Ricinoleate
Skin Conditioning, Emollient
Butylene Glycol
Skin Conditioning, Humectant

Benefits

Good for dry skin

Concerns

Contains paraben
Contains silicone
Not fungal acne (malassezia) safe

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Diphenylsiloxy Phenyl Trimethicone
Antifoaming agent, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Antifoaming agentHair conditioningSkin conditioning
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Polymethylsilsesquioxane
Opacifying
Low-hazard ingredient.Read moreShow less
EWG 1 Opacifying
Dimethicone/Phenyl Vinyl Dimethicone Crosspolymer
Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Viscosity controlling
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion stabilising, Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 Emulsion stabilisingViscosity controlling
Glyceryl Ricinoleate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningEmollientEmulsifyingSurfactant
Dimethyl Isosorbide
Solvent, Viscosity decreasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 SolventViscosity decreasing agentViscosity controlling
Squalane
Emollient, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientHair conditioningRefattingSkin conditioning
Caprylyl Glycol
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningEmollientHumectant
Ceramide NP
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Hair conditioningSkin conditioning
Gluconolactone
Fragrance, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceHumectantSolvent
Zinc PCA
Skin conditioning, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 3 Skin conditioningHumectant
Dimethyl MEA
Ph adjuster, Buffering agent
Low-to-moderate hazard.Read moreShow less
EWG 4 Ph adjusterBuffering agent
Sorbitan Isostearate
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmulsifyingSurfactant
+ 13 more — see the full ingredients list above
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone
Glyceryl Stearate
Emollient, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientEmulsifying Fungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Polysorbate 60
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Morning & evening: Suitable for both AM and PM use.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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