Peptide 21 Wrinkle Resist Serum
The Peter Thomas Roth Peptide 21 Wrinkle Resist Serum is a serums, essence, ampoule. Our analysis of its 56 ingredients (49 low-risk) rates it Excellent (98/100). Based on its ingredients, it looks well-suited to dry skin.
The Peter Thomas Roth Peptide 21 Wrinkle Resist Serum is a serums, essence, ampoule. Our analysis of its 56 ingredients (49 low-risk) rates it Excellent (98/100). Based on its ingredients, it looks well-suited to dry skin.
Summarised from our ingredient analysis — not brand marketing copy.
The evidence
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
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Water
(Solvent) |
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Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent) |
Good for Dry Skin
Fungal Acne Trigger
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Rosa Centifolia Flower Water
(Skin Conditioning, Skin Protecting) |
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Isopropyl Myristate
(Binding Agent, Fragrance, Skin Conditioning, Emollient, Binding, Perfuming, Solvent) |
Bad for Oily Skin
Fungal Acne Trigger
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Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning) |
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Mannitol
(Binding Agent, Flavoring Agent, Humectant, Binding, Masking, Moisturising, Skin Conditioning) |
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Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling) |
Good for Dry Skin
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Natto Gum
(Viscosity Increasing Agent, Film Forming) |
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Tripeptide-10 Citrulline
(Skin Conditioning) |
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Acetyl Octapeptide-3
(Humectant, Skin Conditioning) |
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Palmitoyl Hexapeptide-12
(Skin Conditioning) |
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Acetyl Tetrapeptide-11
(Skin Conditioning) |
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Acetyl Hexapeptide-8
(Humectant, Skin Conditioning) |
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Acetyl Hexapeptide-1
(Skin Conditioning) |
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Palmitoyl Oligopeptide
(Skin Conditioning, Sufactant) |
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Acetyl Tetrapeptide-9
(Skin Conditioning) |
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Acetyl Tetrapeptide-2
(Skin Conditioning) |
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Tripeptide-1
(Skin Conditioning) |
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Palmitoyl Tetrapeptide-7
(Skin Conditioning) |
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Hexapeptide-11
(Skin Conditioning) |
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Dipeptide Diaminobutyroyl Benzylamide Diacetate
(Skin Conditioning) |
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Palmitoyl Tripeptide-5
(Skin Conditioning) |
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Trifluoroacetyl Tripeptide-2
(Skin Conditioning) |
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Palmitoyl Tripeptide-1
(Skin Conditioning) |
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Sodium Polyglutamate
(Hair Conditioning, Skin Conditioning, Humectant) |
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Sodium Hyaluronate
(Skin Conditioning, Humectant) |
Good for Dry Skin
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Tocopheryl Acetate
(Antioxidant, Skin Conditioning) |
Bad for Oily Skin
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Retinyl Palmitate
(Skin Conditioning, Skin Conditioning Miscellaneous) |
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ASCORBIC ACID
(Antioxidant, Buffering, Fragrance, Skin Conditioning) |
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Hydrolyzed Soy Protein
(Antistatic Agent, Hair Conditioning, Humectant, Skin Conditioning) |
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Hydrolyzed Wheat Protein
(Film Forming, Hair Conditioning, Skin Conditioning, Antistatic Agent) |
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Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Antistatic Agent, Emollient) |
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Pseudoalteromonas Ferment Extract
(Humectant) |
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Acrylates Copolymer
(Adhesive, Artificial Nail Builder, Binding Agent, Film Forming, Hair Fixing, Suspending Agent Nonsurfactant, Antistatic Agent, Binding) |
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Magnesium Chloride
(Viscosity Controlling) |
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Polysorbate 20
(Emulsifying, Surfactant) |
Fungal Acne Trigger
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Dimethyl Isosorbide
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling) |
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Acrylates/C10-30 Alkyl Acrylate Crosspolymer
(Emulsion Stabilising, Film Forming, Viscosity Controlling) |
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Leuconostoc/Radish Root Ferment Filtrate
(Antidandruff Agent, Antimicrobial) |
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PEG-8 Dimethicone
(Hair Conditioning, Skin Conditioning) |
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Disodium Phosphate
(Buffering Agent, Anticorrosive, Fragrance, Ph Adjuster, Masking) |
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Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling) |
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Dextran
(Binding Agent, Bulking Agent, Binding, Viscosity Controlling) |
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Sodium Lactate
(Buffering Agent, Exfoliant, Humectant, Keratolytic) |
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Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
(Skin Conditioning) |
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Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling) |
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Triethanolamine
(Fragrance, Ph Adjuster, Emulsifying, Surfactant, Buffering Agent, Masking) |
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Sodium Phosphate
(Buffering Agent) |
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Octyldodecanol
(Fragrance, Skin Conditioning, Emollient, Perfuming, Solvent) |
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Silica
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Opacifying, Viscosity Controlling) |
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Sodium Propoxyhydroxypropyl Thiosulfate Silica
(Bulking Agent) |
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Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent) |
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Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant) |
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Potassium Sorbate
(Fragrance, Preservative) |
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Sodium Benzoate
(Fragrance, Preservative, Anticorrosive, Masking) |
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Phenoxyethanol
(Fragrance, Preservative) |
Paraben
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No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.
How to use
General guidance from this product's category and active ingredients — always follow the directions on the package.
Trust & honesty
Contains ingredients some choose to avoid or double-check while pregnant or nursing.
Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.
This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.
The concentrations these actives are typically effective at in research — not a measurement of this product.
Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.
Retinyl Palmitate
L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.
ASCORBIC ACID
INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.
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