Peter Thomas Roth FIRMx Growth Factor Extreme Neuropeptide Serum

Peter Thomas Roth

Peter Thomas Roth FIRMx Growth Factor Extreme Neuropeptide Serum

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About this product

The Peter Thomas Roth FIRMx Growth Factor Extreme Neuropeptide Serum is a serums, essence, ampoule. Our analysis of its 48 ingredients (41 low-risk) rates it Excellent (94/100). Based on its ingredients, it looks well-suited to dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
48
Low-risk
41
Fragrance
Fragrance-free
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 17/7
Good for dry skin
Dimethiconol Squalane Ethylhexyl Cocoate Isohexadecane Caprylic/Capric Triglyceride Caprylyl Glycol Butylene Glycol Sodium PCA Sodium Hyaluronate Glycerin Propylene Glycol Trehalose Polyquaternium-51 Hexapeptide-10 Dimethicone Cyclopentasiloxane Urea
Caution for dry skin
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Glycerin Acrylates Copolymer Laureth-3 Polysorbate 20 Polysorbate 80 Silica
Oily/Acne-Prone Skin No data
Sensitive Skin 6/11
Good for sensitive skin
Glutamylamidoethyl Indole Ascorbyl Palmitate Glycerin Dimethicone Tocopheryl Acetate Acetyl hexapeptide-22
Caution for sensitive skin
Dipropylene Glycol Ascorbyl Palmitate Arginine Caprylic/Capric Triglyceride Butylene Glycol Glycerin Propylene Glycol Triacetin Retinyl Palmitate (Vitamin A) Methylparaben Propylparaben

Ingredients list

48 total
Lower hazard (1) Higher hazard (9)
All48 Skin Conditioning32 Humectant14 Film Forming10 Solvent9 Fragrance8 Hair Conditioning8 Viscosity Controlling8 Emollient8
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
A
Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning)
3
A
Cyclopentasiloxane
(Hair Conditioning, Skin Conditioning, Emollient, Solvent)
Silicone
Silicone
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone
1
2
A
Silica
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Opacifying, Viscosity Controlling)
1
A
Dimethiconol
(Antifoaming Agent, Skin Conditioning, Emollient, Moisturising)
Silicone
Silicone
1
B
Sodium PCA
(Hair Conditioning, Humectant, Antistatic Agent, Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
3
A
Urea
(Buffering Agent, Humectant, Antistatic Agent, Skin Conditioning)
1
B
Ethylhexyl Cocoate
(Skin Conditioning, Emollient)
Fungal Acne
Fungal Acne Trigger
1
Hexapeptide-10
(Humectant)
1
Myristoyl Pentapeptide-17
(Skin Conditioning)
1
Palmitoyl Hexapeptide-19
(Skin Conditioning)
Acetyl hexapeptide-22
(Antioxidant, Reducing, Skin Protecting)
1
Quercus Suber Bark Extract
(Skin Conditioning)
1
B
Hydrolyzed Oats
(Hair Conditioning, Skin Conditioning, Antistatic Agent)
1
Acetyl Dipeptide-1 Cetyl Ester
(Hair Conditioning, Skin Conditioning)
9
Retinyl Palmitate (Vitamin A) Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
1
A
Ascorbyl Palmitate
(Antioxidant, Masking)
Fungal Acne
Fungal Acne Trigger
1
A
Arginine
(Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Masking)
1
A
Phospholipids
(Skin Conditioning)
Dimethylmethoxy Chromanyl Palmitate
(Skin Conditioning)
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
B
Isohexadecane
(Skin Conditioning, Emollient, Solvent)
1
Ammonium Polyacryloyldimethyl Taurate
(Emulsion Stabilising, Viscosity Increasing Agent, Viscosity Controlling)
Glycerin/Isophthalic Acid Copolymer Castorate
(Film Forming)
1
Polysilicone-11
(Film Forming)
1
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
(Anticaking Agent, Emulsion Stabilising, Opacifying, Suspending Agent Nonsurfactant, Viscosity Increasing Agent)
3
B
Polysorbate 80
(Denaturant, Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
A
Trehalose
(Flavoring Agent, Humectant, Moisturising)
1
Polyquaternium-51
(Film Forming, Humectant, Skin Conditioning)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
1
A
Triacetin
(Cosmetic Biocide, Fragrance, Plasticizer, Solvent, Antimicrobial, Film Forming, Masking)
2
B
Acrylates Copolymer
(Adhesive, Artificial Nail Builder, Binding Agent, Film Forming, Hair Fixing, Suspending Agent Nonsurfactant, Antistatic Agent, Binding)
1
A
Dextran
(Binding Agent, Bulking Agent, Binding, Viscosity Controlling)
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
1
A
Dipropylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Masking, Viscosity Controlling)
3
B
Laureth-3
(Emulsifying, Surfactant)
1
A
Hydroxyethylcellulose
(Binding Agent, Emulsion Stabilising, Film Forming, Viscosity Increasing Agent, Binding, Stabilising, Viscosity Controlling)
3
B
Propylene Glycol
(Fragrance, Humectant, Skin Conditioningagent Miscellaneous, Solvent, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
6
B
Diazolidinyl Urea
(Preservative)
4
A
Methylparaben
(Fragrance, Preservative)
Paraben
Paraben
7
A
Propylparaben
(Fragrance, Preservative, Perfuming)
Paraben
Paraben
1
Glutamylamidoethyl Indole
(Skin Protecting)

My Ingredient Notes

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Key ingredients

Glycerin
Humectant, Skin Protecting
Caprylic/Capric Triglyceride
Emollient, Skin Conditioning
Butylene Glycol
Skin Conditioning, Humectant
Squalane
Emollient, Skin Conditioning
Cyclopentasiloxane
Skin Conditioning, Emollient
Dimethicone
Skin Protecting, Emollient

Benefits

Good for dry skin

Concerns

Contains paraben
Contains silicone
Not fungal acne (malassezia) safe
Retinyl Palmitate (Vitamin A) — higher EWG
Propylparaben — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
Squalane
Emollient, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientHair conditioningRefattingSkin conditioning
Silica
Abrasive, Absorbent
Low-hazard ingredient.Read moreShow less
EWG 1–2 CIR A AbrasiveAbsorbentAnticaking agentBulking agentOpacifyingViscosity controlling
Urea
Buffering agent, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Buffering agentHumectantAntistatic agentSkin conditioning
Hexapeptide-10
Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 Humectant
Myristoyl Pentapeptide-17
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Palmitoyl Hexapeptide-19
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Acetyl hexapeptide-22
Antioxidant, Reducing
Limited public safety data.Read moreShow less
EWG N/A AntioxidantReducingSkin protecting
Quercus Suber Bark Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Hydrolyzed Oats
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Hair conditioningSkin conditioningAntistatic agent
Acetyl Dipeptide-1 Cetyl Ester
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Hair conditioningSkin conditioning
Arginine
Fragrance, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceHair conditioningSkin conditioningAntistatic agentMasking
Phospholipids
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Dimethylmethoxy Chromanyl Palmitate
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
+ 16 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Cyclopentasiloxane
Hair conditioning, Skin conditioning
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Hair conditioningSkin conditioningEmollientSolvent Silicone
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone
Dimethiconol
Antifoaming agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antifoaming agentSkin conditioningEmollientMoisturising Silicone
Sodium PCA
Hair conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Hair conditioningHumectantAntistatic agentSkin conditioning Good for Dry Skin
Ethylhexyl Cocoate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioningEmollient Fungal-acne trigger
Retinyl Palmitate (Vitamin A)
Other
Higher-hazard ingredient.Read moreShow less
EWG 9 Good for Dry SkinFungal-acne trigger
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Ascorbyl Palmitate
Antioxidant, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A AntioxidantMasking Fungal-acne trigger
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Polysorbate 80
Denaturant, Emulsifying
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B DenaturantEmulsifyingSurfactant Fungal-acne trigger
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Propylene Glycol
Fragrance, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B FragranceHumectantSkin-conditioningagent - miscellaneousSolventViscosity decreasing agentSkin conditioningViscosity controlling Good for Dry Skin
Diazolidinyl Urea
Preservative
Moderate-hazard ingredient.Read moreShow less
EWG 6 CIR B Preservative
+ 2 more — see the full ingredients list above

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinyl Palmitate (Vitamin A))

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinyl Palmitate (Vitamin A)

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

Ascorbyl Palmitate

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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