Retinol 10X Regenerate Dry Serum

Replenix

Where to buy Possibly in stock

About this product

The Replenix Retinol 10X Regenerate Dry Serum is a serums, essence, ampoule. Our analysis of its 12 ingredients (9 low-risk) rates it Excellent (92/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
12
Low-risk
9
Fragrance
Fragrance-free
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe Minimal Ingredients

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 4/2
Good for dry skin
Sodium Hyaluronate Cyclomethicone Cyclopentasiloxane PEG-12 Dimethicone/PPG-20 Crosspolymer
Caution for dry skin
Dimethicone Crosspolymer Polysorbate 20
Oily/Acne-Prone Skin 1/0
Good for oily/acne-prone skin
Retinol
Sensitive Skin 0/2
Caution for sensitive skin
Caffeine Retinol

Ingredients list

12 total
Lower hazard (1) Higher hazard (9)
All12 Skin Conditioning11 Emollient3 Humectant2 Emulsifying2 Viscosity Controlling2 Hair Fixing2 Emulsion Stabilising2 Solvent2
EWG CIR Ingredient Name & Cosmetic Functions Notes
3
A
Cyclopentasiloxane
(Hair Conditioning, Skin Conditioning, Emollient, Solvent)
Silicone
Silicone
1
Caprylyl Methicone
(Skin Conditioning)
1
A
Dimethicone Crosspolymer
(Emulsion Stabilising, Hair Fixing, Suspending Agent Nonsurfactant, Viscosity Increasingagent Nonaqueous, Viscosity Controlling)
A
PEG-12 Dimethicone/PPG-20 Crosspolymer
(Emollient, Skin Conditioning)
2
Disiloxane
(Antifoaming Agent, Skin Conditioning)
1
Caffeine
(Fragrance, Skin Conditioning, Masking)
3
A
PEG/PPG-18/18 Dimethicone
(Emulsifying)
Camellia Sinensis Polyphenols
(Antioxidant)
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
2
A
Cyclomethicone
(Antistatic Agent, Emollient, Hair Conditioning, Humectant, Solvent, Viscosity Controlling)
Silicone
Silicone

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Cyclopentasiloxane
Skin Conditioning, Emollient
Caprylyl Methicone
Skin Conditioning
PEG-12 Dimethicone/PPG-20 Crosspolymer
Emollient, Skin Conditioning
Disiloxane
Skin Conditioning
Caffeine
Skin Conditioning
Camellia Sinensis Polyphenols
Antioxidant

Benefits

Good for dry skin
Good for oily/acne-prone skin

Concerns

Contains silicone
Not fungal acne (malassezia) safe
Retinol — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Caprylyl Methicone
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Dimethicone Crosspolymer
Emulsion stabilising, Hair fixing
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingHair fixingSuspending agent - nonsurfactantViscosity increasingagent - nonaqueousViscosity controlling
PEG-12 Dimethicone/PPG-20 Crosspolymer
Emollient, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A CIR A EmollientSkin conditioning
Disiloxane
Antifoaming agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 2 Antifoaming agentSkin conditioning
Caffeine
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceSkin conditioningMasking
PEG/PPG-18/18 Dimethicone
Emulsifying
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Emulsifying
Camellia Sinensis Polyphenols
Antioxidant
Limited public safety data.Read moreShow less
EWG N/A Antioxidant
Cyclopentasiloxane
Hair conditioning, Skin conditioning
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Hair conditioningSkin conditioningEmollientSolvent Silicone
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Cyclomethicone
Antistatic agent, Emollient
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A Antistatic agentEmollientHair conditioningHumectantSolventViscosity controlling Silicone

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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