SkinMedica Retinol Complex .25

SkinMedica

Where to buy Possibly in stock

About this product

The SkinMedica Retinol Complex .25 is a treatment. Our analysis of its 34 ingredients (31 low-risk) rates it Excellent (96/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Treatments
Ingredients
34
Low-risk
31
Fragrance
Fragrance-free
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 10/5
Good for dry skin
Dicaprylyl Ether Lauryl Alcohol Cetyl Ethylhexanoate Cetyl Palmitate Squalane Squalene Caprylic/Capric Triglyceride Butylene Glycol Glycerin Glycine Soja (Soybean) Oil
Caution for dry skin
Glycerin Laureth-23 Sodium Hydroxide Polysorbate 20 Trideceth-6 Phosphate
Oily/Acne-Prone Skin 1/0
Good for oily/acne-prone skin
Retinol
Sensitive Skin 4/8
Good for sensitive skin
Glycerin Glycine Soja (Soybean) Oil Magnolia Grandiflora Bark Extract Tocopheryl Acetate
Caution for sensitive skin
Cetyl Palmitate Caprylic/Capric Triglyceride Butylene Glycol Glycerin Glycine Soja (Soybean) Oil Potassium Sorbate Phenoxyethanol Retinol

Ingredients list

34 total
Lower hazard (1) Higher hazard (9)
All34 Skin Conditioning24 Emollient8 Fragrance6 Solvent5 Viscosity Controlling5 Hair Conditioning4 Emulsifying4 Antioxidant3
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
B
Cetyl Ethylhexanoate
(Skin Conditioning, Emollient)
1
A
Glycine Soja (Soybean) Oil
(Antioxidant, Fragrance, Emollient, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
Fungal Acne
Fungal Acne Trigger
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
2
Polyacrylate-13
(Film Forming)
1
A
Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning)
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
Palmitoyl Tripeptide-8
(Skin Conditioning)
1
Dunaliella Salina Extract
(Skin Conditioning)
1
Magnolia Grandiflora Bark Extract
(Antimicrobial, Antioxidant, Skin Conditioning)
1
Tocopherol (Vitamin E) Good for Dry Skin
Good for Dry Skin
1
A
Tocotrienols
(Oral Care Agent, Skin Conditioning, Uv Absorber)
1
Ceramide
1
(-)-alpha-isabolol
1
A
Phytosterols
(Skin Conditioning)
1
A
Squalene
(Hair Conditioning, Skin Conditioning, Emollient, Antistatic Agent, Refatting)
Fungal Acne
Fungal Acne Trigger
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
2
A
Oryza Sativa (Rice) Bran
(Abrasive, Bulking Agent)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
B
Cetyl Palmitate
(Fragrance, Emollient, Masking, Skin Conditioning)
3
B
Laureth-23
(Cleansing, Emulsifying, Surfactant)
Bad for Oily Skin
Bad for Oily Skin
Trideceth-6 Phosphate
(Emulsifying, Surfactant)
3
B
Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent)
1
Dicaprylyl Ether
(Skin Conditioning, Emollient, Solvent)
1
Lauryl Alcohol
(Emollient, Emulsifying, Emulsion Stabilising, Viscosity Controlling)
1
A
Polyisobutene
(Binding Agent, Film Forming, Viscosity Increasing Agent, Binding, Viscosity Controlling)
1
A
Dextran
(Binding Agent, Bulking Agent, Binding, Viscosity Controlling)
3
A
Potassium Sorbate
(Fragrance, Preservative)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Cetyl Ethylhexanoate
Skin Conditioning, Emollient
Glycine Soja (Soybean) Oil
Antioxidant, Emollient
Niacinamide
Skin Conditioning
Squalane
Emollient, Skin Conditioning
Retinol
Skin Conditioning
Palmitoyl Tripeptide-8
Skin Conditioning

Benefits

Good for dry skin
Good for oily/acne-prone skin

Concerns

Contains paraben
Not fungal acne (malassezia) safe
Retinol — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Cetyl Ethylhexanoate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioningEmollient
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Polyacrylate-13
Film forming
Low-hazard ingredient.Read moreShow less
EWG 2 Film forming
Squalane
Emollient, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientHair conditioningRefattingSkin conditioning
Palmitoyl Tripeptide-8
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Dunaliella Salina Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Magnolia Grandiflora Bark Extract
Antimicrobial, Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 AntimicrobialAntioxidantSkin conditioning
Tocotrienols
Oral care agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Oral care agentSkin conditioningUv absorber
Ceramide
Other
Low-hazard ingredient.Read moreShow less
EWG 1
(-)-alpha-isabolol
Other
Low-hazard ingredient.Read moreShow less
EWG 1
Phytosterols
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Oryza Sativa (Rice) Bran
Abrasive, Bulking agent
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A AbrasiveBulking agent
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
Cetyl Palmitate
Fragrance, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B FragranceEmollientMaskingSkin conditioning
+ 9 more — see the full ingredients list above
Glycine Soja (Soybean) Oil
Antioxidant, Fragrance
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR A AntioxidantFragranceEmollientSkin conditioning Bad for Oily SkinFungal-acne trigger
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Tocopherol (Vitamin E)
Other
Low-hazard ingredient.Read moreShow less
EWG 1 Good for Dry Skin
Squalene
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningEmollientAntistatic agentRefatting Fungal-acne trigger
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Laureth-23
Cleansing, Emulsifying
Potentially comedogenic - can block poresRead moreShow less
EWG 3 CIR B CleansingEmulsifyingSurfactant Bad for Oily Skin
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Morning only: Apply as the last step of your AM routine, after moisturiser, and reapply every ~2 hours of sun exposure.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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