Topix Replenix AE Dermal Restructuring Therapy
The Topix Replenix AE Dermal Restructuring Therapy is a misc. Our analysis of its 41 ingredients (35 low-risk) rates it Excellent (90/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.
The Topix Replenix AE Dermal Restructuring Therapy is a misc. Our analysis of its 41 ingredients (35 low-risk) rates it Excellent (90/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.
Summarised from our ingredient analysis — not brand marketing copy.
The evidence
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
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Water
(Solvent) |
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Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent) |
Good for Dry Skin
Fungal Acne Trigger
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Cetearyl Alcohol
(Emulsion Stabilising, Opacifying, Foam Boosting, Viscosity Increasingagent Aqueous, Viscosity Increasing Agent, Emollient, Emulsifying, Viscosity Controlling) |
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PPG-2 Myristyl Ether Propionate
(Skin Conditioning, Emollient) |
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Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning) |
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Cetyl Alcohol
(Emulsion Stabilising, Fragrance, Opacifying, Emulsifying, Surfactant, Foam Boosting, Viscosity Increasing Agent, Emollient, Masking, Viscosity Controlling) |
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Padina Pavonica Extract
(Skin Conditioning) |
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Disodium Lauriminodipropionate Tocopheryl Phosphates
(Hair Conditioning, Hair Fixing, Skin Conditioning, Surfactant Cleansing Agent, Antistatic Agent, Foaming) |
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Phyllanthus Emblica Extract
(Skin Conditioning) |
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Camellia Sinensis (Green Tea) Leaf Extract
(Antioxidant, Fragrance, Oral Care Agent, Skin Conditioning Agent Miscellaneous, Uv Absorber, Antimicrobial, Astringent, Emollient, Humectant, Masking, Skin Conditioning, Skin Protecting, Tonic) |
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Palmitoyl Pentapeptide-3 | |
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Camellia Sinensis Leaf Extract
(Antimicrobial, Antioxidant, Astringent, Emollient, Humectant, Masking, Oral Care Agent, Skin Conditioning, Skin Protecting, Tonic, Uv Absorber) |
Good for Oily Skin
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Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning) |
Silicone
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Ectoin
(Buffering Agent, Skin Conditioning, Emollient) |
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(-)-alpha-isabolol | |
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Sodium Hyaluronate
(Skin Conditioning, Humectant) |
Good for Dry Skin
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Rubus Idaeus (Raspberry) Seed Oil
(Skin Conditioning, Emollient) |
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Sea Whip Extract
(Skin Conditioning) |
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Phospholipids
(Skin Conditioning) |
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Saccharomyces Lysate Extract
(Humectant, Skin Conditioning) |
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Ascorbyl Palmitate
(Antioxidant, Masking) |
Fungal Acne Trigger
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Tocopheryl Acetate
(Antioxidant, Skin Conditioning) |
Bad for Oily Skin
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Retinyl Palmitate (Vitamin A) |
Good for Dry Skin
Fungal Acne Trigger
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Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent) |
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Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling) |
Good for Dry Skin
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Polysorbate 20
(Emulsifying, Surfactant) |
Fungal Acne Trigger
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Ceramide 2
(Hair Conditioning, Skin Conditioning) |
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Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling) |
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Hydrogenated Polydecene
(Fragrance, Hair Conditioning, Skin Conditioning, Emollient, Solvent) |
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Trideceth-6
(Emulsifying, Surfactant) |
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Sodium Polyacrylate
(Absorbent, Emulsion Stabilising, Film Forming, Hair Fixing, Skin Conditioning Agent Emollient, Viscosity Controlling Agent, Viscosity Increasing Agent, Binding, Skin Conditioning) |
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Ubiquinone
(Antioxidant, Skin Conditioning) |
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Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Antistatic Agent, Emollient) |
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Triethanolamine
(Fragrance, Ph Adjuster, Emulsifying, Surfactant, Buffering Agent, Masking) |
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Polysorbate 60
(Emulsifying, Surfactant) |
Fungal Acne Trigger
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Methylparaben
(Fragrance, Preservative) |
Paraben
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Propylparaben
(Fragrance, Preservative, Perfuming) |
Paraben
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Imidazolidinyl Urea
(Preservative) |
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Disodium EDTA
(Chelating Agent, Viscosity Controlling) |
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Fragrance
(Deodorant, Masking, Perfuming) |
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Superoxide Dismutase
(Reducing, Skin Conditioning, Antioxidant) |
No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.
EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →
How to use
General guidance from this product's category and active ingredients — always follow the directions on the package.
Trust & honesty
Contains ingredients some choose to avoid or double-check while pregnant or nursing.
Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.
This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.
The concentrations these actives are typically effective at in research — not a measurement of this product.
Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.
Retinyl Palmitate (Vitamin A)
L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.
Ascorbyl Palmitate
INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.
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