Advanced Blemish Defence

DS Laboratories

Where to buy Possibly in stock

About this product

The DS Laboratories Advanced Blemish Defence is a serums, essence, ampoule. Our analysis of its 9 ingredients (7 low-risk) rates it Excellent (90/100). Based on its ingredients, it looks well-suited to oily / acne-prone skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
9
Low-risk
7
Fragrance
Fragrance-free
Origin
United States
Data updated
May 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe Minimal Ingredients

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 1/3
Good for dry skin
Propylene Glycol
Caution for dry skin
Salicylic Acid Alcohol Sodium Hydroxide
Oily/Acne-Prone Skin 2/0
Good for oily/acne-prone skin
Salicylic Acid Alcohol
Sensitive Skin 0/3
Caution for sensitive skin
Propylene Glycol Salicylic Acid Alcohol

Ingredients list

9 total
Lower hazard (1) Higher hazard (4)
All9 Skin Conditioning6 Solvent3 Film Forming2 Denaturant2 Buffering Agent2 Ph Adjuster2 Exfoliant2 Humectant2
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
2
Alcohol
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
3
B
Propylene Glycol
(Fragrance, Humectant, Skin Conditioningagent Miscellaneous, Solvent, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
4
B
Glycolic Acid
(Exfoliant, Ph Adjuster, Buffering Agent)
Good for Oily Skin
Good for Oily Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
3
B
Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent)
1
Potassium Azeloyl Diglycinate
(Skin Conditioning)
4
B
Salicylic Acid
(Antiacne Agent, Antidandruff Agent, Corn/Callus/Wart Remover, Denaturant, Exfoliant, Fragrance, Hair Conditioning, Skin Conditioning, Keratolytic, Masking, Preservative)
Good for Oily Skin
Good for Oily Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
1
Silybum Marianum Ethyl Ester
(Skin Conditioning)
1
A
Polyquaternium-10
(Antistatic Agent, Film Forming, Hair Fixing)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

AHA
Exfoliates skin for a brighter complexion.
BHA
Unclogs pores and reduces excess oil.
Azelaic Acid
Gently exfoliates and reduces inflammation.
Exfoliators
Removes dead skin cells to smoothe texture.

Benefits

Good For Oily SkinBalances oil and helps reduce shine.
Acne FightingFights acne and helps prevent breakouts.
BrighteningRestores radiance to dull, tired skin.
Reduces Large PoresMinimizes the look of enlarged pores.
Dark SpotsFades dark spots for even skin tone.
Skin TextureSmooths rough patches and refines texture.
Anti-AgingSoftens lines and helps skin look youthful.
HydratingBoosts hydration and relieves dry, tight skin.

Concerns

May not suit dry skin
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Sodium Hydroxide
Denaturant, Ph adjuster
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B DenaturantPh adjusterBuffering agent
Potassium Azeloyl Diglycinate
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Silybum Marianum Ethyl Ester
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Polyquaternium-10
Antistatic agent, Film forming
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antistatic agentFilm formingHair fixing
Alcohol
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 2 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
Propylene Glycol
Fragrance, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B FragranceHumectantSkin-conditioningagent - miscellaneousSolventViscosity decreasing agentSkin conditioningViscosity controlling Good for Dry Skin
Glycolic Acid
Exfoliant, Ph adjuster
Skin irritation can occur at high concentrationRead moreShow less
EWG 4 CIR B ExfoliantPh adjusterBuffering agent Good for Oily SkinBad for Sensitive Skin
Salicylic Acid
Antiacne agent, Antidandruff agent
Skin irritation can occur at high concentrationRead moreShow less
EWG 4 CIR B Antiacne agentAntidandruff agentCorn/callus/wart removerDenaturantExfoliantFragranceHair conditioningSkin conditioningKeratolyticMaskingPreservative Good for Oily SkinBad for Sensitive Skin

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening, start slow: Best in the PM a few times a week to begin with; avoid layering with other strong actives the same night.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Use with caution
BHA (salicylic) (Salicylic Acid)

Low-strength topical salicylic acid (BHA) is generally considered fine. Caution is usually reserved for high-strength leave-on products and salicylic peels.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

BHA (salicylic) 0.5–2%

Salicylic acid is OTC-capped at 2%; 0.5–2% is the usual leave-on range. Much below that it acts more as a soothing agent than an exfoliant.

Salicylic Acid

AHA (acid exfoliant) 5–10% (OTC)

OTC leave-on AHAs are usually 5–10%. The effect also depends on pH and free-acid value, not the percentage alone.

Glycolic Acid

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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