Cold Plasma Plus+ Advanced Serum Concentrate

Perricone MD

Cold Plasma Plus+ Advanced Serum Concentrate

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About this product

The Perricone MD Cold Plasma Plus+ Advanced Serum Concentrate is a serums, essence, ampoule. Our analysis of its 36 ingredients (28 low-risk) rates it Excellent (96/100). Based on its ingredients, it looks well-suited to dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
36
Low-risk
28
Fragrance
Fragrance-free
Origin
United States

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 9/5
Good for dry skin
Glyceryl Stearate Cetearyl Alcohol Acetyl Hexapeptide-8 Isopropyl Palmitate Caprylyl Glycol Butylene Glycol Sodium Hyaluronate Glycerin Dimethicone
Caution for dry skin
Glycerin Phosphatidylcholine Ceteareth-20 Polysorbate 20 PEG-100 Stearate
Oily/Acne-Prone Skin No data
Sensitive Skin 5/7
Good for sensitive skin
Glycerin Tetrahexyldecyl Ascorbate Copper Gluconate Dimethicone Hydrolyzed Myrtus Communis Leaf Extract
Caution for sensitive skin
Isopropyl Palmitate Butylene Glycol Glycerin Tyrosine Sorbic Acid Potassium Sorbate Phenoxyethanol

Ingredients list

36 total
Lower hazard (1) Higher hazard (4)
All36 Skin Conditioning32 Fragrance9 Humectant6 Viscosity Controlling5 Emulsifying5 Skin Protecting5 Emollient5 Solvent5
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
B
Isopropyl Palmitate
(Binding Agent, Fragrance, Skin Conditioning, Emollient, Antistatic Agent, Binding, Perfuming, Solvent)
Bad for Oily Skin
Bad for Oily Skin
Fungal Acne
Fungal Acne Trigger
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Cetearyl Alcohol
(Emulsion Stabilising, Opacifying, Foam Boosting, Viscosity Increasingagent Aqueous, Viscosity Increasing Agent, Emollient, Emulsifying, Viscosity Controlling)
1
A
Glyceryl Stearate
(Emollient, Emulsifying)
Fungal Acne
Fungal Acne Trigger
3
A
PEG-100 Stearate
(Surfactant)
Fungal Acne
Fungal Acne Trigger
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
A
Phosphatidylcholine
(Skin Conditioning, Emulsifying, Surfactant)
1
Tetrahexyldecyl Ascorbate
(Antioxidant, Skin Conditioning)
4
Dimethyl MEA
(Ph Adjuster, Buffering Agent)
1
Acetyl Hexapeptide-8
(Humectant, Skin Conditioning)
1
A
Palmitoyl Tripeptide-1
(Skin Conditioning)
1
A
Palmitoyl Tetrapeptide-7
(Skin Conditioning)
1
A
Tyrosine
(Fragrance, Hair Conditioning, Proprietary, Skin Conditioning Agent Miscellaneous, Antistatic Agent, Masking, Skin Conditioning)
1
Echium Plantagineum Seed Oil
(Skin Conditioning, Solvent)
4
B
Glycolic Acid
(Exfoliant, Ph Adjuster, Buffering Agent)
Good for Oily Skin
Good for Oily Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
Hydrolyzed Myrtus Communis Leaf Extract
(Skin Protecting)
1
A
Copper Tripeptide-1
(Skin Conditioning)
Helianthus Annuus Seed Oil
(Fragrance, Skin Conditioning, Skin Conditioning Emollient)
1
A
Magnesium Aspartate
(Skin Conditioning)
3
Zinc Gluconate
(Cosmetic Biocide, Skin Conditioning, Deodorant)
2
Copper Gluconate
(Skin Conditioning, Skin Protecting)
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
rosmarinus officinalis leaf extract
(Antimicrobial, Fragrance, Skin Conditioning)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
Retinyl Palmitate
(Skin Conditioning, Skin Conditioning Miscellaneous)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
3
B
Ceteareth-20
(Cleansing, Emulsifying, Surfactant)
Hydrogenated Vegetable Glycerides
(Skin Conditioning, Skin Conditioning Emollient, Surfactant Cleansing, Surfactant Emulsifying, Viscosity Controlling)
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
3
A
Sorbic Acid
(Fragrance, Preservative)
3
A
Potassium Sorbate
(Fragrance, Preservative)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Isopropyl Palmitate
Skin Conditioning, Emollient
Glycerin
Humectant, Skin Protecting
Cetearyl Alcohol
Emollient
Glyceryl Stearate
Emollient
Butylene Glycol
Skin Conditioning, Humectant
Phosphatidylcholine
Skin Conditioning

Benefits

Good for dry skin

Concerns

Contains paraben
Contains silicone
Not fungal acne (malassezia) safe
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Cetearyl Alcohol
Emulsion stabilising, Opacifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingOpacifyingFoam boostingViscosity increasingagent - aqueousViscosity increasing agentEmollientEmulsifyingViscosity controlling
Phosphatidylcholine
Skin conditioning, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningEmulsifyingSurfactant
Tetrahexyldecyl Ascorbate
Antioxidant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 AntioxidantSkin conditioning
Dimethyl MEA
Ph adjuster, Buffering agent
Low-to-moderate hazard.Read moreShow less
EWG 4 Ph adjusterBuffering agent
Acetyl Hexapeptide-8
Humectant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 HumectantSkin conditioning
Palmitoyl Tripeptide-1
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Palmitoyl Tetrapeptide-7
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Tyrosine
Fragrance, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceHair conditioningProprietarySkin-conditioning agent -miscellaneousAntistatic agentMaskingSkin conditioning
Echium Plantagineum Seed Oil
Skin conditioning, Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioningSolvent
Hydrolyzed Myrtus Communis Leaf Extract
Skin protecting
Limited public safety data.Read moreShow less
EWG N/A Skin protecting
Copper Tripeptide-1
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Helianthus Annuus Seed Oil
Fragrance, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A FragranceSkin conditioningSkin conditioning emollient
Magnesium Aspartate
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Zinc Gluconate
Cosmetic biocide, Skin conditioning
Low-to-moderate hazard.Read moreShow less
EWG 3 Cosmetic biocideSkin conditioningDeodorant
+ 11 more — see the full ingredients list above
Isopropyl Palmitate
Binding agent, Fragrance
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR B Binding agentFragranceSkin conditioningEmollientAntistatic agentBindingPerfumingSolvent Bad for Oily SkinFungal-acne trigger
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Glyceryl Stearate
Emollient, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientEmulsifying Fungal-acne trigger
PEG-100 Stearate
Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Surfactant Fungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Glycolic Acid
Exfoliant, Ph adjuster
Skin irritation can occur at high concentrationRead moreShow less
EWG 4 CIR B ExfoliantPh adjusterBuffering agent Good for Oily SkinBad for Sensitive Skin
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinyl Palmitate)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinyl Palmitate

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

Tetrahexyldecyl Ascorbate

AHA (acid exfoliant) 5–10% (OTC)

OTC leave-on AHAs are usually 5–10%. The effect also depends on pH and free-acid value, not the percentage alone.

Glycolic Acid

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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