Sesretinal Liposomal Serum

Sesderma

Where to buy Possibly in stock

About this product

The Sesderma Sesretinal Liposomal Serum is a serums, essence, ampoule. Our analysis of its 61 ingredients (40 low-risk) rates it Excellent (95/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
61
Low-risk
40
Fragrance
Contains fragrance
Origin
Spain

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 12/11
Good for dry skin
C12-15 Alkyl Benzoate Gluconolactone Glyceryl Stearate Cetearyl Alcohol Bidens Pilosa Extract Sodium Hyaluronate Glycerin Cholesterol Hydrogenated Polydecene Bis-PEG-18 Methyl Ether Dimethyl Silane Cyclopentasiloxane Lactic Acid
Caution for dry skin
Sodium Lauroyl Lactylate Lycium Barbarum Fruit Extract Xanthan Gum Glycerin Phosphatidylcholine Ceteth-20 Alcohol Sodium Hydroxide Polysorbate 20 Zinc Chloride Triethanolamine
Oily/Acne-Prone Skin 3/0
Good for oily/acne-prone skin
Lycium Barbarum Fruit Extract Alcohol Zinc Chloride
Sensitive Skin 4/12
Good for sensitive skin
Glycerin Tocopheryl Acetate Zinc Chloride BHT
Caution for sensitive skin
Gluconolactone Sodium Chloride Glycerin Alcohol Tromethamine Hydrogenated Polydecene Sodium Benzoate Potassium Sorbate Lactic Acid Phenoxyethanol Triethanolamine BHT

Ingredients list

61 total
Lower hazard (1) Higher hazard (6)
All61 Skin Conditioning42 Fragrance12 Hair Conditioning11 Ph Adjuster9 Viscosity Controlling9 Buffering Agent8 Emulsifying8 Emulsion Stabilising7
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
3
Bis-PEG-18 Methyl Ether Dimethyl Silane
(Humectant, Foam Boosting, Hydrotrope, Emollient, Hair Conditioning, Skin Conditioning)
2
A
Hydrogenated Polydecene
(Fragrance, Hair Conditioning, Skin Conditioning, Emollient, Solvent)
2
B
Ceteth-20
(Cleansing, Emulsifying, Surfactant)
1
Propanediol
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1
A
C12-15 Alkyl Benzoate
(Skin Conditioning, Emollient, Antimicrobial)
3
A
Cyclopentasiloxane
(Hair Conditioning, Skin Conditioning, Emollient, Solvent)
Silicone
Silicone
1
A
Glyceryl Stearate
(Emollient, Emulsifying)
Fungal Acne
Fungal Acne Trigger
1
Gluconolactone
(Fragrance, Humectant, Solvent)
1
Ammonium Acryloyldimethyltaurate/VP Copolymer
(Viscosity Controlling)
Nicotiana Benthamiana Hexapeptide-40 sh-Oligopeptide-1
(Skin Conditioning)
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-5
(Skin Conditioning)
Nicotiana Benthamiana Sh-Polypeptide-15 Hexapeptide-40
(Skin Conditioning)
2
Alcohol
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
1
Bakuchiol
(Cosmetic Biocide, Antimicrobial)
6
A
BHT
(Antioxidant, Fragrance, Masking)
1
Bidens Pilosa Extract
(Humectant, Skin Conditioning)
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
Ceramide AP
(Hair Conditioning, Skin Conditioning)
Ceramide EOP
(Hair Conditioning, Skin Conditioning)
1
Ceramide NP
(Hair Conditioning, Skin Conditioning)
1
A
Cetearyl Alcohol
(Emulsion Stabilising, Opacifying, Foam Boosting, Viscosity Increasingagent Aqueous, Viscosity Increasing Agent, Emollient, Emulsifying, Viscosity Controlling)
1
A
Cholesterol
(Emulsion Stabilising, Skin Conditioning, Viscosity Increasing Agent, Emollient, Emulsifying, Stabilising, Viscosity Controlling)
Copper Sulfate
(Skin Conditioning)
1
B
Dipotassium Phosphate
(Anticorrosive, Ph Adjuster, Buffering Agent)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
ELAEIS GUINEENSIS OIL
(Skin Conditioning Emollient)
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
1
Glucosamine HCl
(Ph Adjuster, Antistatic Agent, Hair Conditioning)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
4
B
Glycolic Acid
(Exfoliant, Ph Adjuster, Buffering Agent)
Good for Oily Skin
Good for Oily Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Glycyrrhetinic Acid
(Skin Conditioning)
GOSSYPIUM HERBACEUM SEED OIL
(Skin Conditioning)
2
3
Hydrochloric Acid
(Ph Adjuster, Buffering Agent)
4
B
Lactic Acid
(Exfoliant, Fragrance, Humectant, Ph Adjuster, Skin Conditioning Agent Humectant, Skin Conditioning, Buffering Agent)
Bad for Sensitive Skin
Bad for Sensitive Skin
Linum Usitatissimum Seed Oil
(Perfuming, Skin Conditioning)
1
Lycium Barbarum Fruit Extract
(Astringent, Hair Conditioning, Skin Conditioning)
1
Mandelic Acid
(Antimicrobial)
1
A
Niacin
(Hair Conditioning, Skin Conditioning, Antistatic Agent, Smoothing)
Nicotiana Benthamiana Sh-Polypedtide-7
(Skin Conditioning)
PARFUM
(Fragrance, Perfuming)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
1
A
Phosphatidylcholine
(Skin Conditioning, Emulsifying, Surfactant)
1
Phytosphingosine
(Hair Conditioning, Skin Conditioning)
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
B
Potassium Phosphate
(Ph Adjuster, Buffering Agent)
3
A
Potassium Sorbate
(Fragrance, Preservative)
5
6
Retinal
(Skin Conditioning)
Retinyl Palmitate
(Skin Conditioning, Skin Conditioning Miscellaneous)
3
A
Sodium Benzoate
(Fragrance, Preservative, Anticorrosive, Masking)
1
Sodium Chloride
(Bulking Agent, Masking, Oral Care Agent, Viscosity Controlling)
Sodium Cholate
(Skin Conditioning, Skin Protecting)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
3
B
Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent)
1
Sodium Lauroyl Lactylate
(Emulsifying, Surfactant)
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
5
B
Triethanolamine
(Fragrance, Ph Adjuster, Emulsifying, Surfactant, Buffering Agent, Masking)
2
A
Tromethamine
(Fragrance, Ph Adjuster, Buffering Agent, Masking)
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
4
Zinc Chloride
(Cosmetic Astringent, Cosmetic Biocide, Drug Astringent Oral Health Care Drugs, Oralcare Agent, Oral Health Care Drug, Oral Care Agent, Soothing)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Bis-PEG-18 Methyl Ether Dimethyl Silane
Humectant, Emollient
Hydrogenated Polydecene
Skin Conditioning, Emollient
C12-15 Alkyl Benzoate
Skin Conditioning, Emollient
Cyclopentasiloxane
Skin Conditioning, Emollient
Glyceryl Stearate
Emollient
Gluconolactone
Humectant

Benefits

Good for dry skin
Good for oily/acne-prone skin

Concerns

Contains paraben
Contains silicone
Not fungal acne (malassezia) safe
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Bis-PEG-18 Methyl Ether Dimethyl Silane
Humectant, Foam boosting
Low-to-moderate hazard.Read moreShow less
EWG 3 HumectantFoam boostingHydrotropeEmollientHair conditioningSkin conditioning
Hydrogenated Polydecene
Fragrance, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A FragranceHair conditioningSkin conditioningEmollientSolvent
Ceteth-20
Cleansing, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 2 CIR B CleansingEmulsifyingSurfactant
Propanediol
Solvent, Viscosity decreasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 SolventViscosity decreasing agentViscosity controlling
C12-15 Alkyl Benzoate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningEmollientAntimicrobial
Gluconolactone
Fragrance, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceHumectantSolvent
Ammonium Acryloyldimethyltaurate/VP Copolymer
Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 Viscosity controlling
Nicotiana Benthamiana Hexapeptide-40 sh-Oligopeptide-1
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-5
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Nicotiana Benthamiana Sh-Polypeptide-15 Hexapeptide-40
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Bakuchiol
Cosmetic biocide, Antimicrobial
Low-hazard ingredient.Read moreShow less
EWG 1 Cosmetic biocideAntimicrobial
Bidens Pilosa Extract
Humectant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 HumectantSkin conditioning
Carbomer
Emulsion stabilising, Viscosity increasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingViscosity increasing agentGel formingViscosity controlling
Ceramide AP
Hair conditioning, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Hair conditioningSkin conditioning
+ 33 more — see the full ingredients list above
Cyclopentasiloxane
Hair conditioning, Skin conditioning
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Hair conditioningSkin conditioningEmollientSolvent Silicone
Glyceryl Stearate
Emollient, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientEmulsifying Fungal-acne trigger
Alcohol
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 2 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
BHT
Antioxidant, Fragrance
Moderate-hazard ingredient.Read moreShow less
EWG 6 CIR A AntioxidantFragranceMasking
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Glycolic Acid
Exfoliant, Ph adjuster
Skin irritation can occur at high concentrationRead moreShow less
EWG 4 CIR B ExfoliantPh adjusterBuffering agent Good for Oily SkinBad for Sensitive Skin
Lactic Acid
Exfoliant, Fragrance
Skin irritation can occur at high concentrationRead moreShow less
EWG 4 CIR B ExfoliantFragranceHumectantPh adjusterSkin-conditioning agent -humectantSkin conditioningBuffering agent Bad for Sensitive Skin
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Retinal
Skin conditioning
Moderate-hazard ingredient.Read moreShow less
EWG 5–6 Skin conditioning
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Triethanolamine
Fragrance, Ph adjuster
Moderate-hazard ingredient.Read moreShow less
EWG 5 CIR B FragrancePh adjusterEmulsifyingSurfactantBuffering agentMasking

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinal, Retinyl Palmitate)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinal, Retinyl Palmitate

AHA (acid exfoliant) 5–10% (OTC)

OTC leave-on AHAs are usually 5–10%. The effect also depends on pH and free-acid value, not the percentage alone.

Glycolic Acid, Lactic Acid, Mandelic Acid

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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